Anti-PLXB1/ PLXNB1/ PLEXIN-B1 monoclonal antibody

Anti-PLXB1/ PLXNB1/ PLEXIN-B1 antibody for FACS & in-vivo assay

Target products collectionGo to PLXNB1/PLXNB1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1390-Ab-1/ GM-Tg-hg-MP1390-Ab-2Anti-Human PLXNB1 monoclonal antibodyHuman
GM-Tg-rg-MP1390-Ab-1/ GM-Tg-rg-MP1390-Ab-2Anti-Rat PLXNB1 monoclonal antibodyRat
GM-Tg-mg-MP1390-Ab-1/ GM-Tg-mg-MP1390-Ab-2Anti-Mouse PLXNB1 monoclonal antibodyMouse
GM-Tg-cynog-MP1390-Ab-1/ GM-Tg-cynog-MP1390-Ab-2Anti-Cynomolgus/ Rhesus macaque PLXNB1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1390-Ab-1/ GM-Tg-felg-MP1390-Ab-2Anti-Feline PLXNB1 monoclonal antibodyFeline
GM-Tg-cang-MP1390-Ab-1/ GM-Tg-cang-MP1390-Ab-2Anti-Canine PLXNB1 monoclonal antibodyCanine
GM-Tg-bovg-MP1390-Ab-1/ GM-Tg-bovg-MP1390-Ab-2Anti-Bovine PLXNB1 monoclonal antibodyBovine
GM-Tg-equg-MP1390-Ab-1/ GM-Tg-equg-MP1390-Ab-2Anti-Equine PLXNB1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1390-Ab-1/ GM-Tg-hg-MP1390-Ab-2; GM-Tg-rg-MP1390-Ab-1/ GM-Tg-rg-MP1390-Ab-2;
GM-Tg-mg-MP1390-Ab-1/ GM-Tg-mg-MP1390-Ab-2; GM-Tg-cynog-MP1390-Ab-1/ GM-Tg-cynog-MP1390-Ab-2;
GM-Tg-felg-MP1390-Ab-1/ GM-Tg-felg-MP1390-Ab-2; GM-Tg-cang-MP1390-Ab-1/ GM-Tg-cang-MP1390-Ab-2;
GM-Tg-bovg-MP1390-Ab-1/ GM-Tg-bovg-MP1390-Ab-2; GM-Tg-equg-MP1390-Ab-1/ GM-Tg-equg-MP1390-Ab-2
Products NameAnti-PLXNB1 monoclonal antibody
Formatmab
Target NamePLXNB1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PLXNB1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PLXB1/ PLXNB1/ PLEXIN-B1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1390
    Target NamePLXNB1
    Gene ID5364,235611,316009,709802,476636,101087385,616798,100053891
    Gene Symbol and Synonyms2900002G15Rik,mKIAA0407,PLEXIN-B1,PLXN5,PLXNB1,SEP
    Uniprot AccessionO43157
    Uniprot Entry NamePLXB1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseOvary Cancer
    Gene EnsemblENSG00000164050
    Target ClassificationN/A

    The target: PLXNB1, gene name: PLXNB1, also named as PLEXIN-B1, PLXN5, SEP. Enables semaphorin receptor activity. Involved in several processes, including negative regulation of cell adhesion; regulation of cell shape; and semaphorin-plexin signaling pathway. Is integral component of plasma membrane. Part of semaphorin receptor complex. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.