Anti-PLXC1/ PLXNC1/ CD232 monoclonal antibody

Anti-PLXC1/ PLXNC1/ CD232 antibody for FACS & in-vivo assay

Target products collectionGo to PLXNC1/PLXNC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1392-Ab-1/ GM-Tg-hg-MP1392-Ab-2Anti-Human PLXNC1 monoclonal antibodyHuman
GM-Tg-rg-MP1392-Ab-1/ GM-Tg-rg-MP1392-Ab-2Anti-Rat PLXNC1 monoclonal antibodyRat
GM-Tg-mg-MP1392-Ab-1/ GM-Tg-mg-MP1392-Ab-2Anti-Mouse PLXNC1 monoclonal antibodyMouse
GM-Tg-cynog-MP1392-Ab-1/ GM-Tg-cynog-MP1392-Ab-2Anti-Cynomolgus/ Rhesus macaque PLXNC1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1392-Ab-1/ GM-Tg-felg-MP1392-Ab-2Anti-Feline PLXNC1 monoclonal antibodyFeline
GM-Tg-cang-MP1392-Ab-1/ GM-Tg-cang-MP1392-Ab-2Anti-Canine PLXNC1 monoclonal antibodyCanine
GM-Tg-bovg-MP1392-Ab-1/ GM-Tg-bovg-MP1392-Ab-2Anti-Bovine PLXNC1 monoclonal antibodyBovine
GM-Tg-equg-MP1392-Ab-1/ GM-Tg-equg-MP1392-Ab-2Anti-Equine PLXNC1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1392-Ab-1/ GM-Tg-hg-MP1392-Ab-2; GM-Tg-rg-MP1392-Ab-1/ GM-Tg-rg-MP1392-Ab-2;
GM-Tg-mg-MP1392-Ab-1/ GM-Tg-mg-MP1392-Ab-2; GM-Tg-cynog-MP1392-Ab-1/ GM-Tg-cynog-MP1392-Ab-2;
GM-Tg-felg-MP1392-Ab-1/ GM-Tg-felg-MP1392-Ab-2; GM-Tg-cang-MP1392-Ab-1/ GM-Tg-cang-MP1392-Ab-2;
GM-Tg-bovg-MP1392-Ab-1/ GM-Tg-bovg-MP1392-Ab-2; GM-Tg-equg-MP1392-Ab-1/ GM-Tg-equg-MP1392-Ab-2
Products NameAnti-PLXNC1 monoclonal antibody
Formatmab
Target NamePLXNC1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PLXNC1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PLXC1/ PLXNC1/ CD232 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1392
    Target NamePLXNC1
    Gene ID10154,54712,362873,711320,100685138,101090275,518168,100064706
    Gene Symbol and Synonyms2510048K12Rik,CD232,PLXN-C1,PLXNC1,VESPR
    Uniprot AccessionO60486
    Uniprot Entry NamePLXC1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000136040
    Target ClassificationN/A

    The target: PLXNC1, gene name: PLXNC1, also named as CD232, PLXN-C1, VESPR. This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jan 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.