Anti-PLXD1/ PLXND1/ PLEXD1 monoclonal antibody

Anti-PLXD1/ PLXND1/ PLEXD1 antibody for FACS & in-vivo assay

Target products collectionGo to PLXND1/PLXND1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1393-Ab-1/ GM-Tg-hg-MP1393-Ab-2Anti-Human PLXND1 monoclonal antibodyHuman
GM-Tg-rg-MP1393-Ab-1/ GM-Tg-rg-MP1393-Ab-2Anti-Rat PLXND1 monoclonal antibodyRat
GM-Tg-mg-MP1393-Ab-1/ GM-Tg-mg-MP1393-Ab-2Anti-Mouse PLXND1 monoclonal antibodyMouse
GM-Tg-cynog-MP1393-Ab-1/ GM-Tg-cynog-MP1393-Ab-2Anti-Cynomolgus/ Rhesus macaque PLXND1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1393-Ab-1/ GM-Tg-felg-MP1393-Ab-2Anti-Feline PLXND1 monoclonal antibodyFeline
GM-Tg-cang-MP1393-Ab-1/ GM-Tg-cang-MP1393-Ab-2Anti-Canine PLXND1 monoclonal antibodyCanine
GM-Tg-bovg-MP1393-Ab-1/ GM-Tg-bovg-MP1393-Ab-2Anti-Bovine PLXND1 monoclonal antibodyBovine
GM-Tg-equg-MP1393-Ab-1/ GM-Tg-equg-MP1393-Ab-2Anti-Equine PLXND1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1393-Ab-1/ GM-Tg-hg-MP1393-Ab-2; GM-Tg-rg-MP1393-Ab-1/ GM-Tg-rg-MP1393-Ab-2;
GM-Tg-mg-MP1393-Ab-1/ GM-Tg-mg-MP1393-Ab-2; GM-Tg-cynog-MP1393-Ab-1/ GM-Tg-cynog-MP1393-Ab-2;
GM-Tg-felg-MP1393-Ab-1/ GM-Tg-felg-MP1393-Ab-2; GM-Tg-cang-MP1393-Ab-1/ GM-Tg-cang-MP1393-Ab-2;
GM-Tg-bovg-MP1393-Ab-1/ GM-Tg-bovg-MP1393-Ab-2; GM-Tg-equg-MP1393-Ab-1/ GM-Tg-equg-MP1393-Ab-2
Products NameAnti-PLXND1 monoclonal antibody
Formatmab
Target NamePLXND1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PLXND1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PLXD1/ PLXND1/ PLEXD1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1393
    Target NamePLXND1
    Gene ID23129,67784,312652,704044,476526,101082890,781625,100056548
    Gene Symbol and Synonyms6230425C21Rik,b2b1863Clo,b2b553Clo,CHTD9,PLEXD1,PLXND1
    Uniprot AccessionQ9Y4D7
    Uniprot Entry NamePLXD1_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000004399
    Target ClassificationN/A

    The target: PLXND1, gene name: PLXND1, also named as PLEXD1. Enables protein domain specific binding activity. Predicted to be involved in several processes, including endothelial cell migration; nervous system development; and regulation of angiogenesis. Predicted to act upstream of or within several processes, including circulatory system development; dichotomous subdivision of terminal units involved in salivary gland branching; and positive regulation of protein binding activity. Located in lamellipodium. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.