Anti-PLPP3/ Dri42/ LPP3 monoclonal antibody

Anti-PLPP3/ Dri42/ LPP3 antibody for FACS & in-vivo assay

Target products collectionGo to PLPP3/PLPP3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1400-Ab-1/ GM-Tg-hg-MP1400-Ab-2Anti-Human PLPP3 monoclonal antibodyHuman
GM-Tg-rg-MP1400-Ab-1/ GM-Tg-rg-MP1400-Ab-2Anti-Rat PLPP3 monoclonal antibodyRat
GM-Tg-mg-MP1400-Ab-1/ GM-Tg-mg-MP1400-Ab-2Anti-Mouse PLPP3 monoclonal antibodyMouse
GM-Tg-cynog-MP1400-Ab-1/ GM-Tg-cynog-MP1400-Ab-2Anti-Cynomolgus/ Rhesus macaque PLPP3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1400-Ab-1/ GM-Tg-felg-MP1400-Ab-2Anti-Feline PLPP3 monoclonal antibodyFeline
GM-Tg-cang-MP1400-Ab-1/ GM-Tg-cang-MP1400-Ab-2Anti-Canine PLPP3 monoclonal antibodyCanine
GM-Tg-bovg-MP1400-Ab-1/ GM-Tg-bovg-MP1400-Ab-2Anti-Bovine PLPP3 monoclonal antibodyBovine
GM-Tg-equg-MP1400-Ab-1/ GM-Tg-equg-MP1400-Ab-2Anti-Equine PLPP3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1400-Ab-1/ GM-Tg-hg-MP1400-Ab-2; GM-Tg-rg-MP1400-Ab-1/ GM-Tg-rg-MP1400-Ab-2;
GM-Tg-mg-MP1400-Ab-1/ GM-Tg-mg-MP1400-Ab-2; GM-Tg-cynog-MP1400-Ab-1/ GM-Tg-cynog-MP1400-Ab-2;
GM-Tg-felg-MP1400-Ab-1/ GM-Tg-felg-MP1400-Ab-2; GM-Tg-cang-MP1400-Ab-1/ GM-Tg-cang-MP1400-Ab-2;
GM-Tg-bovg-MP1400-Ab-1/ GM-Tg-bovg-MP1400-Ab-2; GM-Tg-equg-MP1400-Ab-1/ GM-Tg-equg-MP1400-Ab-2
Products NameAnti-PLPP3 monoclonal antibody
Formatmab
Target NamePLPP3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PLPP3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PLPP3/ Dri42/ LPP3 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1400
    Target NamePLPP3
    Gene ID8613,67916,192270,715993,479557,101095760,617707,100049896
    Gene Symbol and Synonyms1110003O22Rik,2610002D05Rik,D4Bwg0538e,D4Bwg1535e,Dri42,LPP3,PAP2B,PLPP3,Ppab2b,PPAP2B,PRG-2,VCIP
    Uniprot AccessionO14495,P97544,Q3SZE3
    Uniprot Entry NamePLPP3_HUMAN,PLPP3_RAT,PLPP3_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000162407
    Target ClassificationN/A

    The target: PLPP3, gene name: PLPP3, also named as Dri42, LPP3, PAP2B, PPAP2B, VCIP. The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is a membrane glycoprotein localized at the cell plasma membrane. It has been shown to actively hydrolyze extracellular lysophosphatidic acid and short-chain phosphatidic acid. The expression of this gene is found to be enhanced by epidermal growth factor in Hela cells. [provided by RefSeq, Mar 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.