Anti-™G2/ PRRG2/ PRGP2 monoclonal antibody

Anti-™G2/ PRRG2/ PRGP2 antibody for FACS & in-vivo assay

Target products collectionGo to PRRG2/PRRG2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1410-Ab-1/ GM-Tg-hg-MP1410-Ab-2Anti-Human PRRG2 monoclonal antibodyHuman
GM-Tg-rg-MP1410-Ab-1/ GM-Tg-rg-MP1410-Ab-2Anti-Rat PRRG2 monoclonal antibodyRat
GM-Tg-mg-MP1410-Ab-1/ GM-Tg-mg-MP1410-Ab-2Anti-Mouse PRRG2 monoclonal antibodyMouse
GM-Tg-cynog-MP1410-Ab-1/ GM-Tg-cynog-MP1410-Ab-2Anti-Cynomolgus/ Rhesus macaque PRRG2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1410-Ab-1/ GM-Tg-felg-MP1410-Ab-2Anti-Feline PRRG2 monoclonal antibodyFeline
GM-Tg-cang-MP1410-Ab-1/ GM-Tg-cang-MP1410-Ab-2Anti-Canine PRRG2 monoclonal antibodyCanine
GM-Tg-bovg-MP1410-Ab-1/ GM-Tg-bovg-MP1410-Ab-2Anti-Bovine PRRG2 monoclonal antibodyBovine
GM-Tg-equg-MP1410-Ab-1/ GM-Tg-equg-MP1410-Ab-2Anti-Equine PRRG2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1410-Ab-1/ GM-Tg-hg-MP1410-Ab-2; GM-Tg-rg-MP1410-Ab-1/ GM-Tg-rg-MP1410-Ab-2;
GM-Tg-mg-MP1410-Ab-1/ GM-Tg-mg-MP1410-Ab-2; GM-Tg-cynog-MP1410-Ab-1/ GM-Tg-cynog-MP1410-Ab-2;
GM-Tg-felg-MP1410-Ab-1/ GM-Tg-felg-MP1410-Ab-2; GM-Tg-cang-MP1410-Ab-1/ GM-Tg-cang-MP1410-Ab-2;
GM-Tg-bovg-MP1410-Ab-1/ GM-Tg-bovg-MP1410-Ab-2; GM-Tg-equg-MP1410-Ab-1/ GM-Tg-equg-MP1410-Ab-2
Products NameAnti-PRRG2 monoclonal antibody
Formatmab
Target NamePRRG2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PRRG2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species ™G2/ PRRG2/ PRGP2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1410
    Target NamePRRG2
    Gene ID5639,65116,361570,719318,100855529,101096431,511235,100055647
    Gene Symbol and Synonyms1600014G02Rik,2510041M06Rik,N4WBP1,PRGP2,PRRG2
    Uniprot AccessionO14669
    Uniprot Entry Name™G2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000126460
    Target ClassificationN/A

    The target: PRRG2, gene name: PRRG2, also named as PRGP2. The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.