Anti-TEST/ PRSS21/ ESP-1 monoclonal antibody

Anti-TEST/ PRSS21/ ESP-1 antibody for FACS & in-vivo assay

Target products collectionGo to PRSS21/PRSS21 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1414-Ab-1/ GM-Tg-hg-MP1414-Ab-2Anti-Human PRSS21 monoclonal antibodyHuman
GM-Tg-rg-MP1414-Ab-1/ GM-Tg-rg-MP1414-Ab-2Anti-Rat PRSS21 monoclonal antibodyRat
GM-Tg-mg-MP1414-Ab-1/ GM-Tg-mg-MP1414-Ab-2Anti-Mouse PRSS21 monoclonal antibodyMouse
GM-Tg-cynog-MP1414-Ab-1/ GM-Tg-cynog-MP1414-Ab-2Anti-Cynomolgus/ Rhesus macaque PRSS21 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1414-Ab-1/ GM-Tg-felg-MP1414-Ab-2Anti-Feline PRSS21 monoclonal antibodyFeline
GM-Tg-cang-MP1414-Ab-1/ GM-Tg-cang-MP1414-Ab-2Anti-Canine PRSS21 monoclonal antibodyCanine
GM-Tg-bovg-MP1414-Ab-1/ GM-Tg-bovg-MP1414-Ab-2Anti-Bovine PRSS21 monoclonal antibodyBovine
GM-Tg-equg-MP1414-Ab-1/ GM-Tg-equg-MP1414-Ab-2Anti-Equine PRSS21 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1414-Ab-1/ GM-Tg-hg-MP1414-Ab-2; GM-Tg-rg-MP1414-Ab-1/ GM-Tg-rg-MP1414-Ab-2;
GM-Tg-mg-MP1414-Ab-1/ GM-Tg-mg-MP1414-Ab-2; GM-Tg-cynog-MP1414-Ab-1/ GM-Tg-cynog-MP1414-Ab-2;
GM-Tg-felg-MP1414-Ab-1/ GM-Tg-felg-MP1414-Ab-2; GM-Tg-cang-MP1414-Ab-1/ GM-Tg-cang-MP1414-Ab-2;
GM-Tg-bovg-MP1414-Ab-1/ GM-Tg-bovg-MP1414-Ab-2; GM-Tg-equg-MP1414-Ab-1/ GM-Tg-equg-MP1414-Ab-2
Products NameAnti-PRSS21 monoclonal antibody
Formatmab
Target NamePRSS21
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PRSS21 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species TEST/ PRSS21/ ESP-1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1414
    Target NamePRSS21
    Gene ID10942,699296,528479
    Gene Symbol and SynonymsESP-1,ESP1,PRSS21,TEST1,TESTISIN
    Uniprot AccessionQ9Y6M0
    Uniprot Entry NameTEST_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000007038
    Target ClassificationN/A

    The target: PRSS21, gene name: PRSS21, also named as ESP-1, ESP1, TEST1, TESTISIN. This gene encodes a cell-surface anchored serine protease, which is a member of the trypsin family of serine proteases. The encoded protein is predicted to be active on peptide linkages involving the carboxyl group of lysine or arginine. The encoded protein localizes to the cytoplasm and the plasma membrane of premeiotic testicular germ cells and may be involved in progression of testicular tumors of germ cell origin. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.