Anti-PRTG/ IGDCC5 monoclonal antibody

Anti-PRTG/ IGDCC5 antibody for FACS & in-vivo assay

Target products collectionGo to PRTG/PRTG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1416-Ab-1/ GM-Tg-hg-MP1416-Ab-2Anti-Human PRTG monoclonal antibodyHuman
GM-Tg-rg-MP1416-Ab-1/ GM-Tg-rg-MP1416-Ab-2Anti-Rat PRTG monoclonal antibodyRat
GM-Tg-mg-MP1416-Ab-1/ GM-Tg-mg-MP1416-Ab-2Anti-Mouse PRTG monoclonal antibodyMouse
GM-Tg-cynog-MP1416-Ab-1/ GM-Tg-cynog-MP1416-Ab-2Anti-Cynomolgus/ Rhesus macaque PRTG monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1416-Ab-1/ GM-Tg-felg-MP1416-Ab-2Anti-Feline PRTG monoclonal antibodyFeline
GM-Tg-cang-MP1416-Ab-1/ GM-Tg-cang-MP1416-Ab-2Anti-Canine PRTG monoclonal antibodyCanine
GM-Tg-bovg-MP1416-Ab-1/ GM-Tg-bovg-MP1416-Ab-2Anti-Bovine PRTG monoclonal antibodyBovine
GM-Tg-equg-MP1416-Ab-1/ GM-Tg-equg-MP1416-Ab-2Anti-Equine PRTG monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1416-Ab-1/ GM-Tg-hg-MP1416-Ab-2; GM-Tg-rg-MP1416-Ab-1/ GM-Tg-rg-MP1416-Ab-2;
GM-Tg-mg-MP1416-Ab-1/ GM-Tg-mg-MP1416-Ab-2; GM-Tg-cynog-MP1416-Ab-1/ GM-Tg-cynog-MP1416-Ab-2;
GM-Tg-felg-MP1416-Ab-1/ GM-Tg-felg-MP1416-Ab-2; GM-Tg-cang-MP1416-Ab-1/ GM-Tg-cang-MP1416-Ab-2;
GM-Tg-bovg-MP1416-Ab-1/ GM-Tg-bovg-MP1416-Ab-2; GM-Tg-equg-MP1416-Ab-1/ GM-Tg-equg-MP1416-Ab-2
Products NameAnti-PRTG monoclonal antibody
Formatmab
Target NamePRTG
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PRTG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PRTG/ IGDCC5 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1416
    Target NamePRTG
    Gene ID283659,235472,315806,698623,487569,101090020,540856,100069087
    Gene Symbol and SynonymsA230098A12Rik,IGDCC5,PRTG,RGD1307157
    Uniprot AccessionQ2VWP7,Q2VWP9
    Uniprot Entry NamePRTG_HUMAN,PRTG_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000166450
    Target ClassificationN/A

    The target: PRTG, gene name: PRTG, also named as IGDCC5. This gene encodes a member of the immunoglobulin superfamily. The encoded transmembrane protein has been associated with the development of various tissues, especially neurogenesis. It has been suggested that this gene may be associated with attention deficit hyperactivity disorder (ADHD). [provided by RefSeq, Nov 2014].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.