Anti-PTN5/ PTPN5/ PTPSTEP monoclonal antibody

Anti-PTN5/ PTPN5/ PTPSTEP antibody for FACS & in-vivo assay

Target products collectionGo to PTPN5/PTPN5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1425-Ab-1/ GM-Tg-hg-MP1425-Ab-2Anti-Human PTPN5 monoclonal antibodyHuman
GM-Tg-rg-MP1425-Ab-1/ GM-Tg-rg-MP1425-Ab-2Anti-Rat PTPN5 monoclonal antibodyRat
GM-Tg-mg-MP1425-Ab-1/ GM-Tg-mg-MP1425-Ab-2Anti-Mouse PTPN5 monoclonal antibodyMouse
GM-Tg-cynog-MP1425-Ab-1/ GM-Tg-cynog-MP1425-Ab-2Anti-Cynomolgus/ Rhesus macaque PTPN5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1425-Ab-1/ GM-Tg-felg-MP1425-Ab-2Anti-Feline PTPN5 monoclonal antibodyFeline
GM-Tg-cang-MP1425-Ab-1/ GM-Tg-cang-MP1425-Ab-2Anti-Canine PTPN5 monoclonal antibodyCanine
GM-Tg-bovg-MP1425-Ab-1/ GM-Tg-bovg-MP1425-Ab-2Anti-Bovine PTPN5 monoclonal antibodyBovine
GM-Tg-equg-MP1425-Ab-1/ GM-Tg-equg-MP1425-Ab-2Anti-Equine PTPN5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1425-Ab-1/ GM-Tg-hg-MP1425-Ab-2; GM-Tg-rg-MP1425-Ab-1/ GM-Tg-rg-MP1425-Ab-2;
GM-Tg-mg-MP1425-Ab-1/ GM-Tg-mg-MP1425-Ab-2; GM-Tg-cynog-MP1425-Ab-1/ GM-Tg-cynog-MP1425-Ab-2;
GM-Tg-felg-MP1425-Ab-1/ GM-Tg-felg-MP1425-Ab-2; GM-Tg-cang-MP1425-Ab-1/ GM-Tg-cang-MP1425-Ab-2;
GM-Tg-bovg-MP1425-Ab-1/ GM-Tg-bovg-MP1425-Ab-2; GM-Tg-equg-MP1425-Ab-1/ GM-Tg-equg-MP1425-Ab-2
Products NameAnti-PTPN5 monoclonal antibody
Formatmab
Target NamePTPN5
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PTPN5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PTN5/ PTPN5/ PTPSTEP VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm003020mouse Ptpn5 Lentivirus plasmid
    ORF Viral VectorvGMLPm003020mouse Ptpn5 Lentivirus particle


    Target information

    Target IDGM-MP1425
    Target NamePTPN5
    Gene ID84867,19259,29644,708151,485409,101081668,615850,100071930
    Gene Symbol and SynonymsPTPN5,PTPSTEP,STEP,STEP61
    Uniprot AccessionP54829,P35234
    Uniprot Entry NamePTN5_HUMAN,PTN5_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000110786
    Target ClassificationN/A

    The target: PTPN5, gene name: PTPN5, also named as PTPSTEP, STEP, STEP61. Enables phosphotyrosine residue binding activity. Predicted to be involved in peptidyl-tyrosine dephosphorylation. Predicted to act upstream of or within protein dephosphorylation. Predicted to be located in nucleoplasm. Predicted to be integral component of membrane. Biomarker of Alzheimer's disease. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.