Anti-PTCA/ PTPRCAP/ CD45-AP monoclonal antibody

Anti-PTCA/ PTPRCAP/ CD45-AP antibody for FACS & in-vivo assay

Target products collectionGo to PTPRCAP/PTPRCAP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1427-Ab-1/ GM-Tg-hg-MP1427-Ab-2Anti-Human PTPRCAP monoclonal antibodyHuman
GM-Tg-rg-MP1427-Ab-1/ GM-Tg-rg-MP1427-Ab-2Anti-Rat PTPRCAP monoclonal antibodyRat
GM-Tg-mg-MP1427-Ab-1/ GM-Tg-mg-MP1427-Ab-2Anti-Mouse PTPRCAP monoclonal antibodyMouse
GM-Tg-cynog-MP1427-Ab-1/ GM-Tg-cynog-MP1427-Ab-2Anti-Cynomolgus/ Rhesus macaque PTPRCAP monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1427-Ab-1/ GM-Tg-felg-MP1427-Ab-2Anti-Feline PTPRCAP monoclonal antibodyFeline
GM-Tg-cang-MP1427-Ab-1/ GM-Tg-cang-MP1427-Ab-2Anti-Canine PTPRCAP monoclonal antibodyCanine
GM-Tg-bovg-MP1427-Ab-1/ GM-Tg-bovg-MP1427-Ab-2Anti-Bovine PTPRCAP monoclonal antibodyBovine
GM-Tg-equg-MP1427-Ab-1/ GM-Tg-equg-MP1427-Ab-2Anti-Equine PTPRCAP monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1427-Ab-1/ GM-Tg-hg-MP1427-Ab-2; GM-Tg-rg-MP1427-Ab-1/ GM-Tg-rg-MP1427-Ab-2;
GM-Tg-mg-MP1427-Ab-1/ GM-Tg-mg-MP1427-Ab-2; GM-Tg-cynog-MP1427-Ab-1/ GM-Tg-cynog-MP1427-Ab-2;
GM-Tg-felg-MP1427-Ab-1/ GM-Tg-felg-MP1427-Ab-2; GM-Tg-cang-MP1427-Ab-1/ GM-Tg-cang-MP1427-Ab-2;
GM-Tg-bovg-MP1427-Ab-1/ GM-Tg-bovg-MP1427-Ab-2; GM-Tg-equg-MP1427-Ab-1/ GM-Tg-equg-MP1427-Ab-2
Products NameAnti-PTPRCAP monoclonal antibody
Formatmab
Target NamePTPRCAP
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-PTPRCAP benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species PTCA/ PTPRCAP/ CD45-AP VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1427
    Target NamePTPRCAP
    Gene ID5790,19265,499300,100424226,106557461,101080917,618341,100053058
    Gene Symbol and SynonymsCD-45-AP,CD45-AP,LPAP,LSM-1,PTPRCAP
    Uniprot AccessionQ14761
    Uniprot Entry NamePTCA_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000213402
    Target ClassificationN/A

    The target: PTPRCAP, gene name: PTPRCAP, also named as CD45-AP, LPAP. The protein encoded by this gene was identified as a transmembrane phosphoprotein specifically associated with tyrosine phosphatase PTPRC/CD45, a key regulator of T- and B-lymphocyte activation. The interaction with PTPRC may be required for the stable expression of this protein. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.