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Anti-RGPA2/ RALGAPA2/ AS250 monoclonal antibody
Anti-RGPA2/ RALGAPA2/ AS250 antibody for FACS & in-vivo assay
Go to RALGAPA2/RALGAPA2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1450-Ab-1/ GM-Tg-hg-MP1450-Ab-2 | Anti-Human RALGAPA2 monoclonal antibody | Human |
| GM-Tg-rg-MP1450-Ab-1/ GM-Tg-rg-MP1450-Ab-2 | Anti-Rat RALGAPA2 monoclonal antibody | Rat |
| GM-Tg-mg-MP1450-Ab-1/ GM-Tg-mg-MP1450-Ab-2 | Anti-Mouse RALGAPA2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1450-Ab-1/ GM-Tg-cynog-MP1450-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RALGAPA2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1450-Ab-1/ GM-Tg-felg-MP1450-Ab-2 | Anti-Feline RALGAPA2 monoclonal antibody | Feline |
| GM-Tg-cang-MP1450-Ab-1/ GM-Tg-cang-MP1450-Ab-2 | Anti-Canine RALGAPA2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1450-Ab-1/ GM-Tg-bovg-MP1450-Ab-2 | Anti-Bovine RALGAPA2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1450-Ab-1/ GM-Tg-equg-MP1450-Ab-2 | Anti-Equine RALGAPA2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1450-Ab-1/ GM-Tg-hg-MP1450-Ab-2; GM-Tg-rg-MP1450-Ab-1/ GM-Tg-rg-MP1450-Ab-2; GM-Tg-mg-MP1450-Ab-1/ GM-Tg-mg-MP1450-Ab-2; GM-Tg-cynog-MP1450-Ab-1/ GM-Tg-cynog-MP1450-Ab-2; GM-Tg-felg-MP1450-Ab-1/ GM-Tg-felg-MP1450-Ab-2; GM-Tg-cang-MP1450-Ab-1/ GM-Tg-cang-MP1450-Ab-2; GM-Tg-bovg-MP1450-Ab-1/ GM-Tg-bovg-MP1450-Ab-2; GM-Tg-equg-MP1450-Ab-1/ GM-Tg-equg-MP1450-Ab-2 |
| Products Name | Anti-RALGAPA2 monoclonal antibody |
| Format | mab |
| Target Name | RALGAPA2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RALGAPA2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species RGPA2/ RALGAPA2/ AS250 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP1450 |
| Target Name | RALGAPA2 |
| Gene ID | 57186,241694,296211,700311,485747,101083671,507082,100060964 |
| Gene Symbol and Synonyms | A230067G21Rik,AS250,bA287B20.1,C10H20orf74,C20orf74,dJ1049G11,dJ1049G11.4,p220,pp250,RALGAPA2,RGC2,RGD1308023 |
| Uniprot Accession | Q2PPJ7,P86411 |
| Uniprot Entry Name | RGPA2_HUMAN,RGPA2_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000188559 |
| Target Classification | N/A |
The target: RALGAPA2, gene name: RALGAPA2, also named as AS250, C20orf74, bA287B20.1, dJ1049G11, dJ1049G11.4, p220. Predicted to enable GTPase activator activity and protein heterodimerization activity. Predicted to be involved in activation of GTPase activity. Predicted to act upstream of or within Ral protein signal transduction; regulation of exocyst localization; and regulation of protein localization. Located in cytosol and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
