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Anti-TR19L/ RELT/ TNFRSF19L monoclonal antibody
Anti-TR19L/ RELT/ TNFRSF19L antibody for FACS & in-vivo assay
Go to RELT/RELT products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1457-Ab-1/ GM-Tg-hg-MP1457-Ab-2 | Anti-Human RELT monoclonal antibody | Human |
| GM-Tg-rg-MP1457-Ab-1/ GM-Tg-rg-MP1457-Ab-2 | Anti-Rat RELT monoclonal antibody | Rat |
| GM-Tg-mg-MP1457-Ab-1/ GM-Tg-mg-MP1457-Ab-2 | Anti-Mouse RELT monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1457-Ab-1/ GM-Tg-cynog-MP1457-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RELT monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1457-Ab-1/ GM-Tg-felg-MP1457-Ab-2 | Anti-Feline RELT monoclonal antibody | Feline |
| GM-Tg-cang-MP1457-Ab-1/ GM-Tg-cang-MP1457-Ab-2 | Anti-Canine RELT monoclonal antibody | Canine |
| GM-Tg-bovg-MP1457-Ab-1/ GM-Tg-bovg-MP1457-Ab-2 | Anti-Bovine RELT monoclonal antibody | Bovine |
| GM-Tg-equg-MP1457-Ab-1/ GM-Tg-equg-MP1457-Ab-2 | Anti-Equine RELT monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1457-Ab-1/ GM-Tg-hg-MP1457-Ab-2; GM-Tg-rg-MP1457-Ab-1/ GM-Tg-rg-MP1457-Ab-2; GM-Tg-mg-MP1457-Ab-1/ GM-Tg-mg-MP1457-Ab-2; GM-Tg-cynog-MP1457-Ab-1/ GM-Tg-cynog-MP1457-Ab-2; GM-Tg-felg-MP1457-Ab-1/ GM-Tg-felg-MP1457-Ab-2; GM-Tg-cang-MP1457-Ab-1/ GM-Tg-cang-MP1457-Ab-2; GM-Tg-bovg-MP1457-Ab-1/ GM-Tg-bovg-MP1457-Ab-2; GM-Tg-equg-MP1457-Ab-1/ GM-Tg-equg-MP1457-Ab-2 |
| Products Name | Anti-RELT monoclonal antibody |
| Format | mab |
| Target Name | RELT |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RELT benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species TR19L/ RELT/ TNFRSF19L VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP1457 |
| Target Name | RELT |
| Gene ID | 84957,320100,361615,718143,485200,101098820,505716,100065672 |
| Gene Symbol and Synonyms | AI3C,E430021K24Rik,RELT,TNFRSF19L,TRLT |
| Uniprot Accession | Q969Z4 |
| Uniprot Entry Name | TR19L_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000054967 |
| Target Classification | N/A |
The target: RELT, gene name: RELT, also named as TNFRSF19L, TRLT. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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