Anti-RER1 monoclonal antibody

Anti-RER1 antibody for FACS & in-vivo assay

Target products collectionGo to RER1/RER1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1458-Ab-1/ GM-Tg-hg-MP1458-Ab-2Anti-Human RER1 monoclonal antibodyHuman
GM-Tg-rg-MP1458-Ab-1/ GM-Tg-rg-MP1458-Ab-2Anti-Rat RER1 monoclonal antibodyRat
GM-Tg-mg-MP1458-Ab-1/ GM-Tg-mg-MP1458-Ab-2Anti-Mouse RER1 monoclonal antibodyMouse
GM-Tg-cynog-MP1458-Ab-1/ GM-Tg-cynog-MP1458-Ab-2Anti-Cynomolgus/ Rhesus macaque RER1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1458-Ab-1/ GM-Tg-felg-MP1458-Ab-2Anti-Feline RER1 monoclonal antibodyFeline
GM-Tg-cang-MP1458-Ab-1/ GM-Tg-cang-MP1458-Ab-2Anti-Canine RER1 monoclonal antibodyCanine
GM-Tg-bovg-MP1458-Ab-1/ GM-Tg-bovg-MP1458-Ab-2Anti-Bovine RER1 monoclonal antibodyBovine
GM-Tg-equg-MP1458-Ab-1/ GM-Tg-equg-MP1458-Ab-2Anti-Equine RER1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1458-Ab-1/ GM-Tg-hg-MP1458-Ab-2; GM-Tg-rg-MP1458-Ab-1/ GM-Tg-rg-MP1458-Ab-2;
GM-Tg-mg-MP1458-Ab-1/ GM-Tg-mg-MP1458-Ab-2; GM-Tg-cynog-MP1458-Ab-1/ GM-Tg-cynog-MP1458-Ab-2;
GM-Tg-felg-MP1458-Ab-1/ GM-Tg-felg-MP1458-Ab-2; GM-Tg-cang-MP1458-Ab-1/ GM-Tg-cang-MP1458-Ab-2;
GM-Tg-bovg-MP1458-Ab-1/ GM-Tg-bovg-MP1458-Ab-2; GM-Tg-equg-MP1458-Ab-1/ GM-Tg-equg-MP1458-Ab-2
Products NameAnti-RER1 monoclonal antibody
Formatmab
Target NameRER1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-RER1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species RER1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1458
    Target NameRER1
    Gene ID11079,67830,298675,694540,479578,101086990,100125922,100061363
    Gene Symbol and Synonyms1110060F11Rik,5830454N22Rik,RER1,RGD1306324
    Uniprot AccessionO15258,Q498C8,A5PJ65
    Uniprot Entry NameRER1_HUMAN,RER1_RAT,RER1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000157916
    Target ClassificationN/A

    The target: RER1, gene name: RER1, also named as . The protein encoded by this gene is a multi-pass membrane protein that is localized to the golgi apparatus. It is involved in the retention of endoplasmic reticulum (ER) membrane proteins in the ER and retrieval of ER membrane proteins from the early Golgi compartment to facilitate gamma-secretase complex assembly. [provided by RefSeq, Oct 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.