Anti-RERG monoclonal antibody

Anti-RERG antibody for FACS & in-vivo assay

Target products collectionGo to RERG/RERG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1459-Ab-1/ GM-Tg-hg-MP1459-Ab-2Anti-Human RERG monoclonal antibodyHuman
GM-Tg-rg-MP1459-Ab-1/ GM-Tg-rg-MP1459-Ab-2Anti-Rat RERG monoclonal antibodyRat
GM-Tg-mg-MP1459-Ab-1/ GM-Tg-mg-MP1459-Ab-2Anti-Mouse RERG monoclonal antibodyMouse
GM-Tg-cynog-MP1459-Ab-1/ GM-Tg-cynog-MP1459-Ab-2Anti-Cynomolgus/ Rhesus macaque RERG monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1459-Ab-1/ GM-Tg-felg-MP1459-Ab-2Anti-Feline RERG monoclonal antibodyFeline
GM-Tg-cang-MP1459-Ab-1/ GM-Tg-cang-MP1459-Ab-2Anti-Canine RERG monoclonal antibodyCanine
GM-Tg-bovg-MP1459-Ab-1/ GM-Tg-bovg-MP1459-Ab-2Anti-Bovine RERG monoclonal antibodyBovine
GM-Tg-equg-MP1459-Ab-1/ GM-Tg-equg-MP1459-Ab-2Anti-Equine RERG monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1459-Ab-1/ GM-Tg-hg-MP1459-Ab-2; GM-Tg-rg-MP1459-Ab-1/ GM-Tg-rg-MP1459-Ab-2;
GM-Tg-mg-MP1459-Ab-1/ GM-Tg-mg-MP1459-Ab-2; GM-Tg-cynog-MP1459-Ab-1/ GM-Tg-cynog-MP1459-Ab-2;
GM-Tg-felg-MP1459-Ab-1/ GM-Tg-felg-MP1459-Ab-2; GM-Tg-cang-MP1459-Ab-1/ GM-Tg-cang-MP1459-Ab-2;
GM-Tg-bovg-MP1459-Ab-1/ GM-Tg-bovg-MP1459-Ab-2; GM-Tg-equg-MP1459-Ab-1/ GM-Tg-equg-MP1459-Ab-2
Products NameAnti-RERG monoclonal antibody
Formatmab
Target NameRERG
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-RERG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species RERG VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1459
    Target NameRERG
    Gene ID85004,232441,502916,700567,486665,101097741,540025,100064029
    Gene Symbol and SynonymsRERG,RGD1562829
    Uniprot AccessionQ96A58,Q0VCJ7
    Uniprot Entry NameRERG_HUMAN,RERG_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000134533
    Target ClassificationN/A

    The target: RERG, gene name: RERG, also named as . RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.