Anti-RHBG/ SLC42A2 monoclonal antibody

Anti-RHBG/ SLC42A2 antibody for FACS & in-vivo assay

Target products collectionGo to RHBG/RHBG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1462-Ab-1/ GM-Tg-hg-MP1462-Ab-2Anti-Human RHBG monoclonal antibodyHuman
GM-Tg-rg-MP1462-Ab-1/ GM-Tg-rg-MP1462-Ab-2Anti-Rat RHBG monoclonal antibodyRat
GM-Tg-mg-MP1462-Ab-1/ GM-Tg-mg-MP1462-Ab-2Anti-Mouse RHBG monoclonal antibodyMouse
GM-Tg-cynog-MP1462-Ab-1/ GM-Tg-cynog-MP1462-Ab-2Anti-Cynomolgus/ Rhesus macaque RHBG monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1462-Ab-1/ GM-Tg-felg-MP1462-Ab-2Anti-Feline RHBG monoclonal antibodyFeline
GM-Tg-cang-MP1462-Ab-1/ GM-Tg-cang-MP1462-Ab-2Anti-Canine RHBG monoclonal antibodyCanine
GM-Tg-bovg-MP1462-Ab-1/ GM-Tg-bovg-MP1462-Ab-2Anti-Bovine RHBG monoclonal antibodyBovine
GM-Tg-equg-MP1462-Ab-1/ GM-Tg-equg-MP1462-Ab-2Anti-Equine RHBG monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1462-Ab-1/ GM-Tg-hg-MP1462-Ab-2; GM-Tg-rg-MP1462-Ab-1/ GM-Tg-rg-MP1462-Ab-2;
GM-Tg-mg-MP1462-Ab-1/ GM-Tg-mg-MP1462-Ab-2; GM-Tg-cynog-MP1462-Ab-1/ GM-Tg-cynog-MP1462-Ab-2;
GM-Tg-felg-MP1462-Ab-1/ GM-Tg-felg-MP1462-Ab-2; GM-Tg-cang-MP1462-Ab-1/ GM-Tg-cang-MP1462-Ab-2;
GM-Tg-bovg-MP1462-Ab-1/ GM-Tg-bovg-MP1462-Ab-2; GM-Tg-equg-MP1462-Ab-1/ GM-Tg-equg-MP1462-Ab-2
Products NameAnti-RHBG monoclonal antibody
Formatmab
Target NameRHBG
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-RHBG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species RHBG/ SLC42A2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1462
    Target NameRHBG
    Gene ID57127,58176,310625,692069,403538,101084679,282709,100064158
    Gene Symbol and SynonymsRHBG,SLC42A2
    Uniprot AccessionQ9H310,Q68FT6,Q8WNQ6,Q4VUI0,Q95M77
    Uniprot Entry NameRHBG_HUMAN,RHBG_MACMU,RHBG_RAT,RHBG_CANLF,RHBG_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000132677
    Target ClassificationN/A

    The target: RHBG, gene name: RHBG, also named as SLC42A2. This gene encodes one of two non-erythroid members of the Rhesus (Rh) protein family. Non-erythroid Rh protein family members are mainly expressed in the kidney and belong to the methylammonium-ammonium permease/ammonia transporters superfamily. All Rh family proteins are predicted to be transmembrane proteins with 12 membrane spanning domains and intracytoplasmic N- and C-termini. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.