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Anti-RHCE/ CD240CE/ RH monoclonal antibody
Anti-RHCE/ CD240CE/ RH antibody for FACS & in-vivo assay
Go to RHCE/RHCE products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1463-Ab-1/ GM-Tg-hg-MP1463-Ab-2 | Anti-Human RHCE monoclonal antibody | Human |
| GM-Tg-rg-MP1463-Ab-1/ GM-Tg-rg-MP1463-Ab-2 | Anti-Rat RHCE monoclonal antibody | Rat |
| GM-Tg-mg-MP1463-Ab-1/ GM-Tg-mg-MP1463-Ab-2 | Anti-Mouse RHCE monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1463-Ab-1/ GM-Tg-cynog-MP1463-Ab-2 | Anti-Cynomolgus/ Rhesus macaque RHCE monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1463-Ab-1/ GM-Tg-felg-MP1463-Ab-2 | Anti-Feline RHCE monoclonal antibody | Feline |
| GM-Tg-cang-MP1463-Ab-1/ GM-Tg-cang-MP1463-Ab-2 | Anti-Canine RHCE monoclonal antibody | Canine |
| GM-Tg-bovg-MP1463-Ab-1/ GM-Tg-bovg-MP1463-Ab-2 | Anti-Bovine RHCE monoclonal antibody | Bovine |
| GM-Tg-equg-MP1463-Ab-1/ GM-Tg-equg-MP1463-Ab-2 | Anti-Equine RHCE monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1463-Ab-1/ GM-Tg-hg-MP1463-Ab-2; GM-Tg-rg-MP1463-Ab-1/ GM-Tg-rg-MP1463-Ab-2; GM-Tg-mg-MP1463-Ab-1/ GM-Tg-mg-MP1463-Ab-2; GM-Tg-cynog-MP1463-Ab-1/ GM-Tg-cynog-MP1463-Ab-2; GM-Tg-felg-MP1463-Ab-1/ GM-Tg-felg-MP1463-Ab-2; GM-Tg-cang-MP1463-Ab-1/ GM-Tg-cang-MP1463-Ab-2; GM-Tg-bovg-MP1463-Ab-1/ GM-Tg-bovg-MP1463-Ab-2; GM-Tg-equg-MP1463-Ab-1/ GM-Tg-equg-MP1463-Ab-2 |
| Products Name | Anti-RHCE monoclonal antibody |
| Format | mab |
| Target Name | RHCE |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-RHCE benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species RHCE/ CD240CE/ RH VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP1463 |
| Target Name | RHCE |
| Gene ID | 6006,100071320 |
| Gene Symbol and Synonyms | CD240CE,RH,RH30,RH30A,Rh4,RHC,RHCE,RHCe(152N),RHD,RHE,RhIVb(J),RHIXB,RHNA,RHPI,RhVI,RhVIII |
| Uniprot Accession | P18577 |
| Uniprot Entry Name | RHCE_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000188672 |
| Target Classification | N/A |
The target: RHCE, gene name: RHCE, also named as CD240CE, RH, RH30A, RHC, RHCe(152N), RHE, RHIXB, RHNA, RHPI, Rh4, RhIVb(J), RhVI, RhVIII. The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene which encodes both the RhC and RhE antigens on a single polypeptide and a second gene which encodes the RhD protein. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. A mutation in this gene results in amorph-type Rh-null disease. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Aug 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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