Anti-SCAM5/ SCAMP5 monoclonal antibody

Anti-SCAM5/ SCAMP5 antibody for FACS & in-vivo assay

Target products collectionGo to SCAMP5/SCAMP5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1482-Ab-1/ GM-Tg-hg-MP1482-Ab-2Anti-Human SCAMP5 monoclonal antibodyHuman
GM-Tg-rg-MP1482-Ab-1/ GM-Tg-rg-MP1482-Ab-2Anti-Rat SCAMP5 monoclonal antibodyRat
GM-Tg-mg-MP1482-Ab-1/ GM-Tg-mg-MP1482-Ab-2Anti-Mouse SCAMP5 monoclonal antibodyMouse
GM-Tg-cynog-MP1482-Ab-1/ GM-Tg-cynog-MP1482-Ab-2Anti-Cynomolgus/ Rhesus macaque SCAMP5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1482-Ab-1/ GM-Tg-felg-MP1482-Ab-2Anti-Feline SCAMP5 monoclonal antibodyFeline
GM-Tg-cang-MP1482-Ab-1/ GM-Tg-cang-MP1482-Ab-2Anti-Canine SCAMP5 monoclonal antibodyCanine
GM-Tg-bovg-MP1482-Ab-1/ GM-Tg-bovg-MP1482-Ab-2Anti-Bovine SCAMP5 monoclonal antibodyBovine
GM-Tg-equg-MP1482-Ab-1/ GM-Tg-equg-MP1482-Ab-2Anti-Equine SCAMP5 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1482-Ab-1/ GM-Tg-hg-MP1482-Ab-2; GM-Tg-rg-MP1482-Ab-1/ GM-Tg-rg-MP1482-Ab-2;
GM-Tg-mg-MP1482-Ab-1/ GM-Tg-mg-MP1482-Ab-2; GM-Tg-cynog-MP1482-Ab-1/ GM-Tg-cynog-MP1482-Ab-2;
GM-Tg-felg-MP1482-Ab-1/ GM-Tg-felg-MP1482-Ab-2; GM-Tg-cang-MP1482-Ab-1/ GM-Tg-cang-MP1482-Ab-2;
GM-Tg-bovg-MP1482-Ab-1/ GM-Tg-bovg-MP1482-Ab-2; GM-Tg-equg-MP1482-Ab-1/ GM-Tg-equg-MP1482-Ab-2
Products NameAnti-SCAMP5 monoclonal antibody
Formatmab
Target NameSCAMP5
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SCAMP5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SCAM5/ SCAMP5 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1482
    Target NameSCAMP5
    Gene ID192683,56807,65171,710454,478371,101081551,508510,100061807
    Gene Symbol and SynonymsSc5,SCAMP5
    Uniprot AccessionQ8TAC9,Q9JKE3,Q17QF8
    Uniprot Entry NameSCAM5_HUMAN,SCAM5_RAT,SCAM5_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000198794
    Target ClassificationN/A

    The target: SCAMP5, gene name: SCAMP5, also named as . Involved in positive regulation of cytokine production; regulation of vesicle-mediated transport; and response to endoplasmic reticulum stress. Located in Golgi apparatus; plasma membrane; and recycling endosome membrane. Is integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.