Anti-SCTR/ SR monoclonal antibody

Anti-SCTR/ SR antibody for FACS & in-vivo assay

Target products collectionGo to SCTR/SCTR products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1491-Ab-1/ GM-Tg-hg-MP1491-Ab-2Anti-Human SCTR monoclonal antibodyHuman
GM-Tg-rg-MP1491-Ab-1/ GM-Tg-rg-MP1491-Ab-2Anti-Rat SCTR monoclonal antibodyRat
GM-Tg-mg-MP1491-Ab-1/ GM-Tg-mg-MP1491-Ab-2Anti-Mouse SCTR monoclonal antibodyMouse
GM-Tg-cynog-MP1491-Ab-1/ GM-Tg-cynog-MP1491-Ab-2Anti-Cynomolgus/ Rhesus macaque SCTR monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1491-Ab-1/ GM-Tg-felg-MP1491-Ab-2Anti-Feline SCTR monoclonal antibodyFeline
GM-Tg-cang-MP1491-Ab-1/ GM-Tg-cang-MP1491-Ab-2Anti-Canine SCTR monoclonal antibodyCanine
GM-Tg-bovg-MP1491-Ab-1/ GM-Tg-bovg-MP1491-Ab-2Anti-Bovine SCTR monoclonal antibodyBovine
GM-Tg-equg-MP1491-Ab-1/ GM-Tg-equg-MP1491-Ab-2Anti-Equine SCTR monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1491-Ab-1/ GM-Tg-hg-MP1491-Ab-2; GM-Tg-rg-MP1491-Ab-1/ GM-Tg-rg-MP1491-Ab-2;
GM-Tg-mg-MP1491-Ab-1/ GM-Tg-mg-MP1491-Ab-2; GM-Tg-cynog-MP1491-Ab-1/ GM-Tg-cynog-MP1491-Ab-2;
GM-Tg-felg-MP1491-Ab-1/ GM-Tg-felg-MP1491-Ab-2; GM-Tg-cang-MP1491-Ab-1/ GM-Tg-cang-MP1491-Ab-2;
GM-Tg-bovg-MP1491-Ab-1/ GM-Tg-bovg-MP1491-Ab-2; GM-Tg-equg-MP1491-Ab-1/ GM-Tg-equg-MP1491-Ab-2
Products NameAnti-SCTR monoclonal antibody
Formatmab
Target NameSCTR
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SCTR benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SCTR/ SR VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1491
    Target NameSCTR
    Gene ID6344,319229,81779,695182,483883,101085142,523291,100051620
    Gene Symbol and Synonyms6530402O03Rik,SCTR,SEC-R,SR
    Uniprot AccessionP47872,P23811
    Uniprot Entry NameSCTR_HUMAN,SCTR_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000080293
    Target ClassificationGPCR

    The target: SCTR, gene name: SCTR, also named as SR. The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.