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Anti-SDK2 monoclonal antibody
Anti-SDK2 antibody for FACS & in-vivo assay
Go to SDK2/SDK2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1497-Ab-1/ GM-Tg-hg-MP1497-Ab-2 | Anti-Human SDK2 monoclonal antibody | Human |
| GM-Tg-rg-MP1497-Ab-1/ GM-Tg-rg-MP1497-Ab-2 | Anti-Rat SDK2 monoclonal antibody | Rat |
| GM-Tg-mg-MP1497-Ab-1/ GM-Tg-mg-MP1497-Ab-2 | Anti-Mouse SDK2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1497-Ab-1/ GM-Tg-cynog-MP1497-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SDK2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1497-Ab-1/ GM-Tg-felg-MP1497-Ab-2 | Anti-Feline SDK2 monoclonal antibody | Feline |
| GM-Tg-cang-MP1497-Ab-1/ GM-Tg-cang-MP1497-Ab-2 | Anti-Canine SDK2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1497-Ab-1/ GM-Tg-bovg-MP1497-Ab-2 | Anti-Bovine SDK2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1497-Ab-1/ GM-Tg-equg-MP1497-Ab-2 | Anti-Equine SDK2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1497-Ab-1/ GM-Tg-hg-MP1497-Ab-2; GM-Tg-rg-MP1497-Ab-1/ GM-Tg-rg-MP1497-Ab-2; GM-Tg-mg-MP1497-Ab-1/ GM-Tg-mg-MP1497-Ab-2; GM-Tg-cynog-MP1497-Ab-1/ GM-Tg-cynog-MP1497-Ab-2; GM-Tg-felg-MP1497-Ab-1/ GM-Tg-felg-MP1497-Ab-2; GM-Tg-cang-MP1497-Ab-1/ GM-Tg-cang-MP1497-Ab-2; GM-Tg-bovg-MP1497-Ab-1/ GM-Tg-bovg-MP1497-Ab-2; GM-Tg-equg-MP1497-Ab-1/ GM-Tg-equg-MP1497-Ab-2 |
| Products Name | Anti-SDK2 monoclonal antibody |
| Format | mab |
| Target Name | SDK2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SDK2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SDK2 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP1497 |
| Target Name | SDK2 |
| Gene ID | 54549,237979,360652,699027,483283,101095058,100336619,100061116 |
| Gene Symbol and Synonyms | 4632412F08Rik,5330435L01Rik,mKIAA1514,Sdk-2,SDK2 |
| Uniprot Accession | Q58EX2 |
| Uniprot Entry Name | SDK2_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000069188 |
| Target Classification | N/A |
The target: SDK2, gene name: SDK2, also named as . The protein encoded by this gene is a member of the immunoglobulin superfamily. The protein contains two immunoglobulin domains and thirteen fibronectin type III domains. Fibronectin type III domains are present in both extracellular and intracellular proteins and tandem repeats are known to contain binding sites for DNA, heparin and the cell surface. This protein, and a homologous mouse sequence, are very similar to the Drosophila sidekick gene product but the specific function of this superfamily member is not yet known. Evidence for alternative splicing at this gene locus has been observed but the full-length nature of additional variants has not yet been determined. [provided by RefSeq, Jul 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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