Anti-SEM5A/ SEMA5A/ SEMAF monoclonal antibody

Anti-SEM5A/ SEMA5A/ SEMAF antibody for FACS & in-vivo assay

Target products collectionGo to SEMA5A/SEMA5A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1502-Ab-1/ GM-Tg-hg-MP1502-Ab-2Anti-Human SEMA5A monoclonal antibodyHuman
GM-Tg-rg-MP1502-Ab-1/ GM-Tg-rg-MP1502-Ab-2Anti-Rat SEMA5A monoclonal antibodyRat
GM-Tg-mg-MP1502-Ab-1/ GM-Tg-mg-MP1502-Ab-2Anti-Mouse SEMA5A monoclonal antibodyMouse
GM-Tg-cynog-MP1502-Ab-1/ GM-Tg-cynog-MP1502-Ab-2Anti-Cynomolgus/ Rhesus macaque SEMA5A monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1502-Ab-1/ GM-Tg-felg-MP1502-Ab-2Anti-Feline SEMA5A monoclonal antibodyFeline
GM-Tg-cang-MP1502-Ab-1/ GM-Tg-cang-MP1502-Ab-2Anti-Canine SEMA5A monoclonal antibodyCanine
GM-Tg-bovg-MP1502-Ab-1/ GM-Tg-bovg-MP1502-Ab-2Anti-Bovine SEMA5A monoclonal antibodyBovine
GM-Tg-equg-MP1502-Ab-1/ GM-Tg-equg-MP1502-Ab-2Anti-Equine SEMA5A monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1502-Ab-1/ GM-Tg-hg-MP1502-Ab-2; GM-Tg-rg-MP1502-Ab-1/ GM-Tg-rg-MP1502-Ab-2;
GM-Tg-mg-MP1502-Ab-1/ GM-Tg-mg-MP1502-Ab-2; GM-Tg-cynog-MP1502-Ab-1/ GM-Tg-cynog-MP1502-Ab-2;
GM-Tg-felg-MP1502-Ab-1/ GM-Tg-felg-MP1502-Ab-2; GM-Tg-cang-MP1502-Ab-1/ GM-Tg-cang-MP1502-Ab-2;
GM-Tg-bovg-MP1502-Ab-1/ GM-Tg-bovg-MP1502-Ab-2; GM-Tg-equg-MP1502-Ab-1/ GM-Tg-equg-MP1502-Ab-2
Products NameAnti-SEMA5A monoclonal antibody
Formatmab
Target NameSEMA5A
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SEMA5A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SEM5A/ SEMA5A/ SEMAF VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1502
    Target NameSEMA5A
    Gene ID9037,20356,310207,696019,478622,101098118,506636,100054607
    Gene Symbol and Synonyms5930434A13,9130201M22Rik,SEMA5A,SEMAF,semF
    Uniprot AccessionQ13591,D3ZTD8
    Uniprot Entry NameSEM5A_HUMAN,SEM5A_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000112902
    Target ClassificationN/A

    The target: SEMA5A, gene name: SEMA5A, also named as SEMAF, semF. This gene belongs to the semaphorin gene family that encodes membrane proteins containing a semaphorin domain and several thrombospondin type-1 repeats. Members of this family are involved in axonal guidance during neural development. This gene has been implicated as an autism susceptibility gene.[provided by RefSeq, Jan 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.