- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-SEM6D/ SEMA6D monoclonal antibody
Anti-SEM6D/ SEMA6D antibody for FACS & in-vivo assay
Go to SEMA6D/SEMA6D products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1503-Ab-1/ GM-Tg-hg-MP1503-Ab-2 | Anti-Human SEMA6D monoclonal antibody | Human |
| GM-Tg-rg-MP1503-Ab-1/ GM-Tg-rg-MP1503-Ab-2 | Anti-Rat SEMA6D monoclonal antibody | Rat |
| GM-Tg-mg-MP1503-Ab-1/ GM-Tg-mg-MP1503-Ab-2 | Anti-Mouse SEMA6D monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1503-Ab-1/ GM-Tg-cynog-MP1503-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SEMA6D monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1503-Ab-1/ GM-Tg-felg-MP1503-Ab-2 | Anti-Feline SEMA6D monoclonal antibody | Feline |
| GM-Tg-cang-MP1503-Ab-1/ GM-Tg-cang-MP1503-Ab-2 | Anti-Canine SEMA6D monoclonal antibody | Canine |
| GM-Tg-bovg-MP1503-Ab-1/ GM-Tg-bovg-MP1503-Ab-2 | Anti-Bovine SEMA6D monoclonal antibody | Bovine |
| GM-Tg-equg-MP1503-Ab-1/ GM-Tg-equg-MP1503-Ab-2 | Anti-Equine SEMA6D monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1503-Ab-1/ GM-Tg-hg-MP1503-Ab-2; GM-Tg-rg-MP1503-Ab-1/ GM-Tg-rg-MP1503-Ab-2; GM-Tg-mg-MP1503-Ab-1/ GM-Tg-mg-MP1503-Ab-2; GM-Tg-cynog-MP1503-Ab-1/ GM-Tg-cynog-MP1503-Ab-2; GM-Tg-felg-MP1503-Ab-1/ GM-Tg-felg-MP1503-Ab-2; GM-Tg-cang-MP1503-Ab-1/ GM-Tg-cang-MP1503-Ab-2; GM-Tg-bovg-MP1503-Ab-1/ GM-Tg-bovg-MP1503-Ab-2; GM-Tg-equg-MP1503-Ab-1/ GM-Tg-equg-MP1503-Ab-2 |
| Products Name | Anti-SEMA6D monoclonal antibody |
| Format | mab |
| Target Name | SEMA6D |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SEMA6D benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SEM6D/ SEMA6D VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP1503 |
| Target Name | SEMA6D |
| Gene ID | 80031,214968,311384,713885,100855988,101100893,518458,100055875 |
| Gene Symbol and Synonyms | 1110067B02Rik,D330011G23,mKIAA1479,SEMA6D |
| Uniprot Accession | Q8NFY4 |
| Uniprot Entry Name | SEM6D_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000137872 |
| Target Classification | N/A |
The target: SEMA6D, gene name: SEMA6D, also named as . Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
