- • Up to 20% off your first purchase
- • Bulk quantities available
- • Citation Reward application
Sample Application
- Animal health test
- In-vitro diagnostics
- Food & Feed Safety
- Environmental Safety
- New drug discovery
Supports
- Talk to our Expert:
[email protected] -
Talk to our sales:
[email protected]
Protocol Library Download
 |
 |
Anti-SEM7A/ SEMA7A/ CD108 monoclonal antibody
Anti-SEM7A/ SEMA7A/ CD108 antibody for FACS & in-vivo assay
Go to SEMA7A/SEMA7A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1504-Ab-1/ GM-Tg-hg-MP1504-Ab-2 | Anti-Human SEMA7A monoclonal antibody | Human |
| GM-Tg-rg-MP1504-Ab-1/ GM-Tg-rg-MP1504-Ab-2 | Anti-Rat SEMA7A monoclonal antibody | Rat |
| GM-Tg-mg-MP1504-Ab-1/ GM-Tg-mg-MP1504-Ab-2 | Anti-Mouse SEMA7A monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1504-Ab-1/ GM-Tg-cynog-MP1504-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SEMA7A monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1504-Ab-1/ GM-Tg-felg-MP1504-Ab-2 | Anti-Feline SEMA7A monoclonal antibody | Feline |
| GM-Tg-cang-MP1504-Ab-1/ GM-Tg-cang-MP1504-Ab-2 | Anti-Canine SEMA7A monoclonal antibody | Canine |
| GM-Tg-bovg-MP1504-Ab-1/ GM-Tg-bovg-MP1504-Ab-2 | Anti-Bovine SEMA7A monoclonal antibody | Bovine |
| GM-Tg-equg-MP1504-Ab-1/ GM-Tg-equg-MP1504-Ab-2 | Anti-Equine SEMA7A monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1504-Ab-1/ GM-Tg-hg-MP1504-Ab-2; GM-Tg-rg-MP1504-Ab-1/ GM-Tg-rg-MP1504-Ab-2; GM-Tg-mg-MP1504-Ab-1/ GM-Tg-mg-MP1504-Ab-2; GM-Tg-cynog-MP1504-Ab-1/ GM-Tg-cynog-MP1504-Ab-2; GM-Tg-felg-MP1504-Ab-1/ GM-Tg-felg-MP1504-Ab-2; GM-Tg-cang-MP1504-Ab-1/ GM-Tg-cang-MP1504-Ab-2; GM-Tg-bovg-MP1504-Ab-1/ GM-Tg-bovg-MP1504-Ab-2; GM-Tg-equg-MP1504-Ab-1/ GM-Tg-equg-MP1504-Ab-2 |
| Products Name | Anti-SEMA7A monoclonal antibody |
| Format | mab |
| Target Name | SEMA7A |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SEMA7A benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species SEM7A/ SEMA7A/ CD108 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP001729 | human SEMA7A Lentivirus plasmid |
| ORF Viral Vector | vGMLP001729 | human SEMA7A Lentivirus particle |
Target information
| Target ID | GM-MP1504 |
| Target Name | SEMA7A |
| Gene ID | 8482,20361,315711,702185,487644,101088844,614707,100062559 |
| Gene Symbol and Synonyms | 2900057C09Rik,CD108,CDw108,H-Sema K1,H-SEMA-K1,H-Sema-L,JMH,M-Sema-L,PFIC11,sema K1,sema L,SEMA7A,SEMAK1,SEMAL |
| Uniprot Accession | O75326 |
| Uniprot Entry Name | SEM7A_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000138623 |
| Target Classification | N/A |
The target: SEMA7A, gene name: SEMA7A, also named as CD108, CDw108, H-SEMA-K1, H-Sema-L, JMH, SEMAK1, SEMAL. This gene encodes a member of the semaphorin family of proteins. The encoded preproprotein is proteolytically processed to generate the mature glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein. The encoded protein is found on activated lymphocytes and erythrocytes and may be involved in immunomodulatory and neuronal processes. The encoded protein carries the John Milton Hagen (JMH) blood group antigens. Mutations in this gene may be associated with reduced bone mineral density (BMD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
Facebook
LinkedIn
Twitter
