Anti-SERC1/ SERINC1/ TDE1L monoclonal antibody

Anti-SERC1/ SERINC1/ TDE1L antibody for FACS & in-vivo assay

Target products collectionGo to SERINC1/SERINC1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1505-Ab-1/ GM-Tg-hg-MP1505-Ab-2Anti-Human SERINC1 monoclonal antibodyHuman
GM-Tg-rg-MP1505-Ab-1/ GM-Tg-rg-MP1505-Ab-2Anti-Rat SERINC1 monoclonal antibodyRat
GM-Tg-mg-MP1505-Ab-1/ GM-Tg-mg-MP1505-Ab-2Anti-Mouse SERINC1 monoclonal antibodyMouse
GM-Tg-cynog-MP1505-Ab-1/ GM-Tg-cynog-MP1505-Ab-2Anti-Cynomolgus/ Rhesus macaque SERINC1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1505-Ab-1/ GM-Tg-felg-MP1505-Ab-2Anti-Feline SERINC1 monoclonal antibodyFeline
GM-Tg-cang-MP1505-Ab-1/ GM-Tg-cang-MP1505-Ab-2Anti-Canine SERINC1 monoclonal antibodyCanine
GM-Tg-bovg-MP1505-Ab-1/ GM-Tg-bovg-MP1505-Ab-2Anti-Bovine SERINC1 monoclonal antibodyBovine
GM-Tg-equg-MP1505-Ab-1/ GM-Tg-equg-MP1505-Ab-2Anti-Equine SERINC1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1505-Ab-1/ GM-Tg-hg-MP1505-Ab-2; GM-Tg-rg-MP1505-Ab-1/ GM-Tg-rg-MP1505-Ab-2;
GM-Tg-mg-MP1505-Ab-1/ GM-Tg-mg-MP1505-Ab-2; GM-Tg-cynog-MP1505-Ab-1/ GM-Tg-cynog-MP1505-Ab-2;
GM-Tg-felg-MP1505-Ab-1/ GM-Tg-felg-MP1505-Ab-2; GM-Tg-cang-MP1505-Ab-1/ GM-Tg-cang-MP1505-Ab-2;
GM-Tg-bovg-MP1505-Ab-1/ GM-Tg-bovg-MP1505-Ab-2; GM-Tg-equg-MP1505-Ab-1/ GM-Tg-equg-MP1505-Ab-2
Products NameAnti-SERINC1 monoclonal antibody
Formatmab
Target NameSERINC1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SERINC1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SERC1/ SERINC1/ TDE1L VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1505
    Target NameSERINC1
    Gene ID57515,56442,294421,713999,476277,101101470,539993,100067255
    Gene Symbol and Synonyms1500011D18Rik,AIGP-2,LRRGT00191,mKIAA1253,SERINC1,SERINC2,TDE1L,TDE2,™S-2,™S2
    Uniprot AccessionQ9NRX5,Q7TNK0,Q3MHV9
    Uniprot Entry NameSERC1_HUMAN,SERC1_RAT,SERC1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000111897
    Target ClassificationN/A

    The target: SERINC1, gene name: SERINC1, also named as TDE1L, TDE2, ™S-2, ™S2. Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in several processes, including phosphatidylserine metabolic process; positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity; and positive regulation of serine C-palmitoyltransferase activity. Predicted to be located in endoplasmic reticulum membrane and plasma membrane. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.