Anti-SERC3/ SERINC3/ AIGP1 monoclonal antibody

Anti-SERC3/ SERINC3/ AIGP1 antibody for FACS & in-vivo assay

Target products collectionGo to SERINC3/SERINC3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1506-Ab-1/ GM-Tg-hg-MP1506-Ab-2Anti-Human SERINC3 monoclonal antibodyHuman
GM-Tg-rg-MP1506-Ab-1/ GM-Tg-rg-MP1506-Ab-2Anti-Rat SERINC3 monoclonal antibodyRat
GM-Tg-mg-MP1506-Ab-1/ GM-Tg-mg-MP1506-Ab-2Anti-Mouse SERINC3 monoclonal antibodyMouse
GM-Tg-cynog-MP1506-Ab-1/ GM-Tg-cynog-MP1506-Ab-2Anti-Cynomolgus/ Rhesus macaque SERINC3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1506-Ab-1/ GM-Tg-felg-MP1506-Ab-2Anti-Feline SERINC3 monoclonal antibodyFeline
GM-Tg-cang-MP1506-Ab-1/ GM-Tg-cang-MP1506-Ab-2Anti-Canine SERINC3 monoclonal antibodyCanine
GM-Tg-bovg-MP1506-Ab-1/ GM-Tg-bovg-MP1506-Ab-2Anti-Bovine SERINC3 monoclonal antibodyBovine
GM-Tg-equg-MP1506-Ab-1/ GM-Tg-equg-MP1506-Ab-2Anti-Equine SERINC3 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1506-Ab-1/ GM-Tg-hg-MP1506-Ab-2; GM-Tg-rg-MP1506-Ab-1/ GM-Tg-rg-MP1506-Ab-2;
GM-Tg-mg-MP1506-Ab-1/ GM-Tg-mg-MP1506-Ab-2; GM-Tg-cynog-MP1506-Ab-1/ GM-Tg-cynog-MP1506-Ab-2;
GM-Tg-felg-MP1506-Ab-1/ GM-Tg-felg-MP1506-Ab-2; GM-Tg-cang-MP1506-Ab-1/ GM-Tg-cang-MP1506-Ab-2;
GM-Tg-bovg-MP1506-Ab-1/ GM-Tg-bovg-MP1506-Ab-2; GM-Tg-equg-MP1506-Ab-1/ GM-Tg-equg-MP1506-Ab-2
Products NameAnti-SERINC3 monoclonal antibody
Formatmab
Target NameSERINC3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SERINC3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SERC3/ SERINC3/ AIGP1 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm001710mouse Serinc3 Lentivirus plasmid
    ORF Viral VectorvGMLPm001710mouse Serinc3 Lentivirus particle


    Target information

    Target IDGM-MP1506
    Target NameSERINC3
    Gene ID10955,26943,296350,712545,477235,101090933,511861,100070746
    Gene Symbol and SynonymsAIGP1,DIFF33,SBBI99,SERINC3,TDE,TDE1,™S-1
    Uniprot AccessionQ13530,A4FUZ5
    Uniprot Entry NameSERC3_HUMAN,SERC3_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000132824
    Target ClassificationN/A

    The target: SERINC3, gene name: SERINC3, also named as AIGP1, DIFF33, SBBI99, TDE, TDE1, ™S-1. Predicted to enable L-serine transmembrane transporter activity. Involved in defense response to virus; detection of virus; and innate immune response. Predicted to be located in Golgi apparatus. Predicted to be active in membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.