Anti-SERC5/ SERINC5/ C5orf12 monoclonal antibody

Anti-SERC5/ SERINC5/ C5orf12 antibody for FACS & in-vivo assay

Target products collectionGo to SERINC5/SERINC5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1507-Ab-1/ GM-Tg-hg-MP1507-Ab-2Anti-Human SERINC5 monoclonal antibodyHuman
GM-Tg-rg-MP1507-Ab-1/ GM-Tg-rg-MP1507-Ab-2Anti-Rat SERINC5 monoclonal antibodyRat
GM-Tg-mg-MP1507-Ab-1/ GM-Tg-mg-MP1507-Ab-2Anti-Mouse SERINC5 monoclonal antibodyMouse
GM-Tg-cynog-MP1507-Ab-1/ GM-Tg-cynog-MP1507-Ab-2Anti-Cynomolgus/ Rhesus macaque SERINC5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1507-Ab-1/ GM-Tg-felg-MP1507-Ab-2Anti-Feline SERINC5 monoclonal antibodyFeline
GM-Tg-cang-MP1507-Ab-1/ GM-Tg-cang-MP1507-Ab-2Anti-Canine SERINC5 monoclonal antibodyCanine
GM-Tg-bovg-MP1507-Ab-1/ GM-Tg-bovg-MP1507-Ab-2Anti-Bovine SERINC5 monoclonal antibodyBovine
GM-Tg-equg-MP1507-Ab-1/ GM-Tg-equg-MP1507-Ab-2Anti-Equine SERINC5 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1507-Ab-1/ GM-Tg-hg-MP1507-Ab-2; GM-Tg-rg-MP1507-Ab-1/ GM-Tg-rg-MP1507-Ab-2;
GM-Tg-mg-MP1507-Ab-1/ GM-Tg-mg-MP1507-Ab-2; GM-Tg-cynog-MP1507-Ab-1/ GM-Tg-cynog-MP1507-Ab-2;
GM-Tg-felg-MP1507-Ab-1/ GM-Tg-felg-MP1507-Ab-2; GM-Tg-cang-MP1507-Ab-1/ GM-Tg-cang-MP1507-Ab-2;
GM-Tg-bovg-MP1507-Ab-1/ GM-Tg-bovg-MP1507-Ab-2; GM-Tg-equg-MP1507-Ab-1/ GM-Tg-equg-MP1507-Ab-2
Products NameAnti-SERINC5 monoclonal antibody
Formatmab
Target NameSERINC5
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SERINC5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SERC5/ SERINC5/ C5orf12 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1507
    Target NameSERINC5
    Gene ID256987,218442,170907,710413,479168,101089919,504658,100073260
    Gene Symbol and SynonymsA130038L21Rik,AIGP3,C5orf12,SERINC5,TPO1
    Uniprot AccessionQ86VE9,Q63175
    Uniprot Entry NameSERC5_HUMAN,SERC5_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000164300
    Target ClassificationN/A

    The target: SERINC5, gene name: SERINC5, also named as C5orf12, TPO1. Predicted to enable L-serine transmembrane transporter activity. Involved in defense response to virus; detection of virus; and innate immune response. Located in several cellular components, including centrosome; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.