Anti-SIDT1/ SID-1/ SID1 monoclonal antibody

Anti-SIDT1/ SID-1/ SID1 antibody for FACS & in-vivo assay

Target products collectionGo to SIDT1/SIDT1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1514-Ab-1/ GM-Tg-hg-MP1514-Ab-2Anti-Human SIDT1 monoclonal antibodyHuman
GM-Tg-rg-MP1514-Ab-1/ GM-Tg-rg-MP1514-Ab-2Anti-Rat SIDT1 monoclonal antibodyRat
GM-Tg-mg-MP1514-Ab-1/ GM-Tg-mg-MP1514-Ab-2Anti-Mouse SIDT1 monoclonal antibodyMouse
GM-Tg-cynog-MP1514-Ab-1/ GM-Tg-cynog-MP1514-Ab-2Anti-Cynomolgus/ Rhesus macaque SIDT1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1514-Ab-1/ GM-Tg-felg-MP1514-Ab-2Anti-Feline SIDT1 monoclonal antibodyFeline
GM-Tg-cang-MP1514-Ab-1/ GM-Tg-cang-MP1514-Ab-2Anti-Canine SIDT1 monoclonal antibodyCanine
GM-Tg-bovg-MP1514-Ab-1/ GM-Tg-bovg-MP1514-Ab-2Anti-Bovine SIDT1 monoclonal antibodyBovine
GM-Tg-equg-MP1514-Ab-1/ GM-Tg-equg-MP1514-Ab-2Anti-Equine SIDT1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1514-Ab-1/ GM-Tg-hg-MP1514-Ab-2; GM-Tg-rg-MP1514-Ab-1/ GM-Tg-rg-MP1514-Ab-2;
GM-Tg-mg-MP1514-Ab-1/ GM-Tg-mg-MP1514-Ab-2; GM-Tg-cynog-MP1514-Ab-1/ GM-Tg-cynog-MP1514-Ab-2;
GM-Tg-felg-MP1514-Ab-1/ GM-Tg-felg-MP1514-Ab-2; GM-Tg-cang-MP1514-Ab-1/ GM-Tg-cang-MP1514-Ab-2;
GM-Tg-bovg-MP1514-Ab-1/ GM-Tg-bovg-MP1514-Ab-2; GM-Tg-equg-MP1514-Ab-1/ GM-Tg-equg-MP1514-Ab-2
Products NameAnti-SIDT1 monoclonal antibody
Formatmab
Target NameSIDT1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SIDT1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SIDT1/ SID-1/ SID1 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1514
    Target NameSIDT1
    Gene ID54847,320007,288109,709487,100685132,101090638,508259,100061301
    Gene Symbol and SynonymsB830021E24Rik,SID-1,SID1,SIDT1
    Uniprot AccessionQ9NXL6,Q6Q3F5
    Uniprot Entry NameSIDT1_HUMAN,SIDT1_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000072858
    Target ClassificationN/A

    The target: SIDT1, gene name: SIDT1, also named as SID-1, SID1. The protein encoded by this gene belongs to SID1 family of transmembrane dsRNA-gated channels. Family members transport dsRNA into cells and are required for systemic RNA interference. [provided by RefSeq, May 2017].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.