Anti-SIDT2/ CGI-40 monoclonal antibody

Anti-SIDT2/ CGI-40 antibody for FACS & in-vivo assay

Target products collectionGo to SIDT2/SIDT2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1515-Ab-1/ GM-Tg-hg-MP1515-Ab-2Anti-Human SIDT2 monoclonal antibodyHuman
GM-Tg-rg-MP1515-Ab-1/ GM-Tg-rg-MP1515-Ab-2Anti-Rat SIDT2 monoclonal antibodyRat
GM-Tg-mg-MP1515-Ab-1/ GM-Tg-mg-MP1515-Ab-2Anti-Mouse SIDT2 monoclonal antibodyMouse
GM-Tg-cynog-MP1515-Ab-1/ GM-Tg-cynog-MP1515-Ab-2Anti-Cynomolgus/ Rhesus macaque SIDT2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1515-Ab-1/ GM-Tg-felg-MP1515-Ab-2Anti-Feline SIDT2 monoclonal antibodyFeline
GM-Tg-cang-MP1515-Ab-1/ GM-Tg-cang-MP1515-Ab-2Anti-Canine SIDT2 monoclonal antibodyCanine
GM-Tg-bovg-MP1515-Ab-1/ GM-Tg-bovg-MP1515-Ab-2Anti-Bovine SIDT2 monoclonal antibodyBovine
GM-Tg-equg-MP1515-Ab-1/ GM-Tg-equg-MP1515-Ab-2Anti-Equine SIDT2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1515-Ab-1/ GM-Tg-hg-MP1515-Ab-2; GM-Tg-rg-MP1515-Ab-1/ GM-Tg-rg-MP1515-Ab-2;
GM-Tg-mg-MP1515-Ab-1/ GM-Tg-mg-MP1515-Ab-2; GM-Tg-cynog-MP1515-Ab-1/ GM-Tg-cynog-MP1515-Ab-2;
GM-Tg-felg-MP1515-Ab-1/ GM-Tg-felg-MP1515-Ab-2; GM-Tg-cang-MP1515-Ab-1/ GM-Tg-cang-MP1515-Ab-2;
GM-Tg-bovg-MP1515-Ab-1/ GM-Tg-bovg-MP1515-Ab-2; GM-Tg-equg-MP1515-Ab-1/ GM-Tg-equg-MP1515-Ab-2
Products NameAnti-SIDT2 monoclonal antibody
Formatmab
Target NameSIDT2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SIDT2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SIDT2/ CGI-40 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm005178mouse Sidt2 Lentivirus plasmid
    ORF Viral VectorvGMLPm005178mouse Sidt2 Lentivirus particle


    Target information

    Target IDGM-MP1515
    Target NameSIDT2
    Gene ID51092,214597,315617,697321,100856519,101081572,513462,100062652
    Gene Symbol and SynonymsB930096O19,CGI-40,RGD1308311,SIDT2
    Uniprot AccessionQ8NBJ9,D3ZEH5
    Uniprot Entry NameSIDT2_HUMAN,SIDT2_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000149577
    Target ClassificationN/A

    The target: SIDT2, gene name: SIDT2, also named as CGI-40. Predicted to enable several functions, including AP-1 adaptor complex binding activity; AP-2 adaptor complex binding activity; and RNA transmembrane transporter activity. Involved in RNA transport. Located in lysosomal membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.