Anti-SIRB2/ SIRPB2/ PTPN1L monoclonal antibody

Anti-SIRB2/ SIRPB2/ PTPN1L antibody for FACS & in-vivo assay

Target products collectionGo to SIRPB2/SIRPB2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1528-Ab-1/ GM-Tg-hg-MP1528-Ab-2Anti-Human SIRPB2 monoclonal antibodyHuman
GM-Tg-rg-MP1528-Ab-1/ GM-Tg-rg-MP1528-Ab-2Anti-Rat SIRPB2 monoclonal antibodyRat
GM-Tg-mg-MP1528-Ab-1/ GM-Tg-mg-MP1528-Ab-2Anti-Mouse SIRPB2 monoclonal antibodyMouse
GM-Tg-cynog-MP1528-Ab-1/ GM-Tg-cynog-MP1528-Ab-2Anti-Cynomolgus/ Rhesus macaque SIRPB2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1528-Ab-1/ GM-Tg-felg-MP1528-Ab-2Anti-Feline SIRPB2 monoclonal antibodyFeline
GM-Tg-cang-MP1528-Ab-1/ GM-Tg-cang-MP1528-Ab-2Anti-Canine SIRPB2 monoclonal antibodyCanine
GM-Tg-bovg-MP1528-Ab-1/ GM-Tg-bovg-MP1528-Ab-2Anti-Bovine SIRPB2 monoclonal antibodyBovine
GM-Tg-equg-MP1528-Ab-1/ GM-Tg-equg-MP1528-Ab-2Anti-Equine SIRPB2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1528-Ab-1/ GM-Tg-hg-MP1528-Ab-2; GM-Tg-rg-MP1528-Ab-1/ GM-Tg-rg-MP1528-Ab-2;
GM-Tg-mg-MP1528-Ab-1/ GM-Tg-mg-MP1528-Ab-2; GM-Tg-cynog-MP1528-Ab-1/ GM-Tg-cynog-MP1528-Ab-2;
GM-Tg-felg-MP1528-Ab-1/ GM-Tg-felg-MP1528-Ab-2; GM-Tg-cang-MP1528-Ab-1/ GM-Tg-cang-MP1528-Ab-2;
GM-Tg-bovg-MP1528-Ab-1/ GM-Tg-bovg-MP1528-Ab-2; GM-Tg-equg-MP1528-Ab-1/ GM-Tg-equg-MP1528-Ab-2
Products NameAnti-SIRPB2 monoclonal antibody
Formatmab
Target NameSIRPB2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SIRPB2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SIRB2/ SIRPB2/ PTPN1L VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1528
    Target NameSIRPB2
    Gene ID284759,715792,485810,101086551,786236,100146829
    Gene Symbol and SynonymsdJ776F14.2,PTPN1L,PTPNS1L3,SIRPB2,SIRPG
    Uniprot AccessionQ5JXA9
    Uniprot Entry NameSIRB2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000196209
    Target ClassificationN/A

    The target: SIRPB2, gene name: SIRPB2, also named as PTPN1L, PTPNS1L3, dJ776F14.2. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.