Anti-SIRPG/ CD172g/ SIRP-B2 monoclonal antibody

Anti-SIRPG/ CD172g/ SIRP-B2 antibody for FACS & in-vivo assay

Target products collectionGo to SIRPG/SIRPG products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1529-Ab-1/ GM-Tg-hg-MP1529-Ab-2Anti-Human SIRPG monoclonal antibodyHuman
GM-Tg-rg-MP1529-Ab-1/ GM-Tg-rg-MP1529-Ab-2Anti-Rat SIRPG monoclonal antibodyRat
GM-Tg-mg-MP1529-Ab-1/ GM-Tg-mg-MP1529-Ab-2Anti-Mouse SIRPG monoclonal antibodyMouse
GM-Tg-cynog-MP1529-Ab-1/ GM-Tg-cynog-MP1529-Ab-2Anti-Cynomolgus/ Rhesus macaque SIRPG monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1529-Ab-1/ GM-Tg-felg-MP1529-Ab-2Anti-Feline SIRPG monoclonal antibodyFeline
GM-Tg-cang-MP1529-Ab-1/ GM-Tg-cang-MP1529-Ab-2Anti-Canine SIRPG monoclonal antibodyCanine
GM-Tg-bovg-MP1529-Ab-1/ GM-Tg-bovg-MP1529-Ab-2Anti-Bovine SIRPG monoclonal antibodyBovine
GM-Tg-equg-MP1529-Ab-1/ GM-Tg-equg-MP1529-Ab-2Anti-Equine SIRPG monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1529-Ab-1/ GM-Tg-hg-MP1529-Ab-2; GM-Tg-rg-MP1529-Ab-1/ GM-Tg-rg-MP1529-Ab-2;
GM-Tg-mg-MP1529-Ab-1/ GM-Tg-mg-MP1529-Ab-2; GM-Tg-cynog-MP1529-Ab-1/ GM-Tg-cynog-MP1529-Ab-2;
GM-Tg-felg-MP1529-Ab-1/ GM-Tg-felg-MP1529-Ab-2; GM-Tg-cang-MP1529-Ab-1/ GM-Tg-cang-MP1529-Ab-2;
GM-Tg-bovg-MP1529-Ab-1/ GM-Tg-bovg-MP1529-Ab-2; GM-Tg-equg-MP1529-Ab-1/ GM-Tg-equg-MP1529-Ab-2
Products NameAnti-SIRPG monoclonal antibody
Formatmab
Target NameSIRPG
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SIRPG benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species SIRPG/ CD172g/ SIRP-B2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1529
    Target NameSIRPG
    Gene ID55423
    Gene Symbol and SynonymsbA77C3.1,CD172g,SIRP-B2,SIRPB2,SIRPG,SIRPgamma
    Uniprot AccessionQ9P1W8
    Uniprot Entry NameSIRPG_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000089012
    Target ClassificationN/A

    The target: SIRPG, gene name: SIRPG, also named as CD172g, SIRP-B2, SIRPB2, SIRPgamma, bA77C3.1. The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.