Anti-NTCP4/ SLC10A4/ P4 monoclonal antibody

Anti-NTCP4/ SLC10A4/ P4 antibody for FACS & in-vivo assay

Target products collectionGo to SLC10A4/SLC10A4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1531-Ab-1/ GM-Tg-hg-MP1531-Ab-2Anti-Human SLC10A4 monoclonal antibodyHuman
GM-Tg-rg-MP1531-Ab-1/ GM-Tg-rg-MP1531-Ab-2Anti-Rat SLC10A4 monoclonal antibodyRat
GM-Tg-mg-MP1531-Ab-1/ GM-Tg-mg-MP1531-Ab-2Anti-Mouse SLC10A4 monoclonal antibodyMouse
GM-Tg-cynog-MP1531-Ab-1/ GM-Tg-cynog-MP1531-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC10A4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1531-Ab-1/ GM-Tg-felg-MP1531-Ab-2Anti-Feline SLC10A4 monoclonal antibodyFeline
GM-Tg-cang-MP1531-Ab-1/ GM-Tg-cang-MP1531-Ab-2Anti-Canine SLC10A4 monoclonal antibodyCanine
GM-Tg-bovg-MP1531-Ab-1/ GM-Tg-bovg-MP1531-Ab-2Anti-Bovine SLC10A4 monoclonal antibodyBovine
GM-Tg-equg-MP1531-Ab-1/ GM-Tg-equg-MP1531-Ab-2Anti-Equine SLC10A4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1531-Ab-1/ GM-Tg-hg-MP1531-Ab-2; GM-Tg-rg-MP1531-Ab-1/ GM-Tg-rg-MP1531-Ab-2;
GM-Tg-mg-MP1531-Ab-1/ GM-Tg-mg-MP1531-Ab-2; GM-Tg-cynog-MP1531-Ab-1/ GM-Tg-cynog-MP1531-Ab-2;
GM-Tg-felg-MP1531-Ab-1/ GM-Tg-felg-MP1531-Ab-2; GM-Tg-cang-MP1531-Ab-1/ GM-Tg-cang-MP1531-Ab-2;
GM-Tg-bovg-MP1531-Ab-1/ GM-Tg-bovg-MP1531-Ab-2; GM-Tg-equg-MP1531-Ab-1/ GM-Tg-equg-MP1531-Ab-2
Products NameAnti-SLC10A4 monoclonal antibody
Formatmab
Target NameSLC10A4
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC10A4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NTCP4/ SLC10A4/ P4 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1531
    Target NameSLC10A4
    Gene ID201780,231290,305309,705961,100688209,101089103,540151,100061200
    Gene Symbol and SynonymsE130304D01,P4,SLC10A4
    Uniprot AccessionQ96EP9,Q5PT56
    Uniprot Entry NameNTCP4_HUMAN,NTCP4_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000145248
    Target ClassificationN/A

    The target: SLC10A4, gene name: SLC10A4, also named as P4. Predicted to enable bile acid:sodium symporter activity. Predicted to be involved in bile acid and bile salt transport and regulation of neurotransmitter loading into synaptic vesicle. Predicted to act upstream of or within adult behavior and response to xenobiotic stimulus. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in cholinergic synapse; dopaminergic synapse; and serotonergic synapse. Predicted to be integral component of synaptic vesicle membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.