Anti-UT2/ SLC14A2/ HUT2 monoclonal antibody

Anti-UT2/ SLC14A2/ HUT2 antibody for FACS & in-vivo assay

Target products collectionGo to SLC14A2/SLC14A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1540-Ab-1/ GM-Tg-hg-MP1540-Ab-2Anti-Human SLC14A2 monoclonal antibodyHuman
GM-Tg-rg-MP1540-Ab-1/ GM-Tg-rg-MP1540-Ab-2Anti-Rat SLC14A2 monoclonal antibodyRat
GM-Tg-mg-MP1540-Ab-1/ GM-Tg-mg-MP1540-Ab-2Anti-Mouse SLC14A2 monoclonal antibodyMouse
GM-Tg-cynog-MP1540-Ab-1/ GM-Tg-cynog-MP1540-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC14A2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1540-Ab-1/ GM-Tg-felg-MP1540-Ab-2Anti-Feline SLC14A2 monoclonal antibodyFeline
GM-Tg-cang-MP1540-Ab-1/ GM-Tg-cang-MP1540-Ab-2Anti-Canine SLC14A2 monoclonal antibodyCanine
GM-Tg-bovg-MP1540-Ab-1/ GM-Tg-bovg-MP1540-Ab-2Anti-Bovine SLC14A2 monoclonal antibodyBovine
GM-Tg-equg-MP1540-Ab-1/ GM-Tg-equg-MP1540-Ab-2Anti-Equine SLC14A2 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1540-Ab-1/ GM-Tg-hg-MP1540-Ab-2; GM-Tg-rg-MP1540-Ab-1/ GM-Tg-rg-MP1540-Ab-2;
GM-Tg-mg-MP1540-Ab-1/ GM-Tg-mg-MP1540-Ab-2; GM-Tg-cynog-MP1540-Ab-1/ GM-Tg-cynog-MP1540-Ab-2;
GM-Tg-felg-MP1540-Ab-1/ GM-Tg-felg-MP1540-Ab-2; GM-Tg-cang-MP1540-Ab-1/ GM-Tg-cang-MP1540-Ab-2;
GM-Tg-bovg-MP1540-Ab-1/ GM-Tg-bovg-MP1540-Ab-2; GM-Tg-equg-MP1540-Ab-1/ GM-Tg-equg-MP1540-Ab-2
Products NameAnti-SLC14A2 monoclonal antibody
Formatmab
Target NameSLC14A2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC14A2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species UT2/ SLC14A2/ HUT2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1540
    Target NameSLC14A2
    Gene ID8170,27411,54302,695078,101084395,537150
    Gene Symbol and SynonymshUT-A6,HUT2,SLC14A2,Slc14a2T,Slc14a2_v4,testSymbol,UrT1-C,UrT1-D,UT-A1,UT-A2,UT-A3,UT2,UTA,UTR
    Uniprot AccessionQ15849,Q62668
    Uniprot Entry NameUT2_HUMAN,UT2_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000132874
    Target ClassificationN/A

    The target: SLC14A2, gene name: SLC14A2, also named as HUT2, UT-A2, UT2, UTA, UTR, hUT-A6. The protein encoded by this gene belongs to the urea transporter family. In mammalian cells, urea is the chief end product of nitrogen catabolism, and plays an important role in the urinary concentration mechanism. This protein is expressed in the inner medulla of the kidney, and mediates rapid transepithelial urea transport across the inner medullary collecting duct. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.