Anti-MOT11/ SLC16A11/ MCT11 monoclonal antibody

Anti-MOT11/ SLC16A11/ MCT11 antibody for FACS & in-vivo assay

Target products collectionGo to SLC16A11/SLC16A11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1542-Ab-1/ GM-Tg-hg-MP1542-Ab-2Anti-Human SLC16A11 monoclonal antibodyHuman
GM-Tg-rg-MP1542-Ab-1/ GM-Tg-rg-MP1542-Ab-2Anti-Rat SLC16A11 monoclonal antibodyRat
GM-Tg-mg-MP1542-Ab-1/ GM-Tg-mg-MP1542-Ab-2Anti-Mouse SLC16A11 monoclonal antibodyMouse
GM-Tg-cynog-MP1542-Ab-1/ GM-Tg-cynog-MP1542-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC16A11 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1542-Ab-1/ GM-Tg-felg-MP1542-Ab-2Anti-Feline SLC16A11 monoclonal antibodyFeline
GM-Tg-cang-MP1542-Ab-1/ GM-Tg-cang-MP1542-Ab-2Anti-Canine SLC16A11 monoclonal antibodyCanine
GM-Tg-bovg-MP1542-Ab-1/ GM-Tg-bovg-MP1542-Ab-2Anti-Bovine SLC16A11 monoclonal antibodyBovine
GM-Tg-equg-MP1542-Ab-1/ GM-Tg-equg-MP1542-Ab-2Anti-Equine SLC16A11 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1542-Ab-1/ GM-Tg-hg-MP1542-Ab-2; GM-Tg-rg-MP1542-Ab-1/ GM-Tg-rg-MP1542-Ab-2;
GM-Tg-mg-MP1542-Ab-1/ GM-Tg-mg-MP1542-Ab-2; GM-Tg-cynog-MP1542-Ab-1/ GM-Tg-cynog-MP1542-Ab-2;
GM-Tg-felg-MP1542-Ab-1/ GM-Tg-felg-MP1542-Ab-2; GM-Tg-cang-MP1542-Ab-1/ GM-Tg-cang-MP1542-Ab-2;
GM-Tg-bovg-MP1542-Ab-1/ GM-Tg-bovg-MP1542-Ab-2; GM-Tg-equg-MP1542-Ab-1/ GM-Tg-equg-MP1542-Ab-2
Products NameAnti-SLC16A11 monoclonal antibody
Formatmab
Target NameSLC16A11
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC16A11 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MOT11/ SLC16A11/ MCT11 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLPm004388mouse Slc16a11 Lentivirus plasmid
    ORF Viral VectorvGMLPm004388mouse Slc16a11 Lentivirus particle


    Target information

    Target IDGM-MP1542
    Target NameSLC16A11
    Gene ID162515,216867,287450,721775,489460,101095054,618274,100072930
    Gene Symbol and SynonymsMCT 11,MCT11,MNCb-2717,SLC16A11
    Uniprot AccessionQ8NCK7
    Uniprot Entry NameMOT11_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000174326
    Target ClassificationN/A

    The target: SLC16A11, gene name: SLC16A11, also named as MCT11. Enables pyruvate transmembrane transporter activity. Involved in lipid metabolic process. Located in endoplasmic reticulum membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.