Anti-MOT12/ SLC16A12/ CJMG monoclonal antibody

Anti-MOT12/ SLC16A12/ CJMG antibody for FACS & in-vivo assay

Target products collectionGo to SLC16A12/SLC16A12 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1543-Ab-1/ GM-Tg-hg-MP1543-Ab-2Anti-Human SLC16A12 monoclonal antibodyHuman
GM-Tg-rg-MP1543-Ab-1/ GM-Tg-rg-MP1543-Ab-2Anti-Rat SLC16A12 monoclonal antibodyRat
GM-Tg-mg-MP1543-Ab-1/ GM-Tg-mg-MP1543-Ab-2Anti-Mouse SLC16A12 monoclonal antibodyMouse
GM-Tg-cynog-MP1543-Ab-1/ GM-Tg-cynog-MP1543-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC16A12 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1543-Ab-1/ GM-Tg-felg-MP1543-Ab-2Anti-Feline SLC16A12 monoclonal antibodyFeline
GM-Tg-cang-MP1543-Ab-1/ GM-Tg-cang-MP1543-Ab-2Anti-Canine SLC16A12 monoclonal antibodyCanine
GM-Tg-bovg-MP1543-Ab-1/ GM-Tg-bovg-MP1543-Ab-2Anti-Bovine SLC16A12 monoclonal antibodyBovine
GM-Tg-equg-MP1543-Ab-1/ GM-Tg-equg-MP1543-Ab-2Anti-Equine SLC16A12 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1543-Ab-1/ GM-Tg-hg-MP1543-Ab-2; GM-Tg-rg-MP1543-Ab-1/ GM-Tg-rg-MP1543-Ab-2;
GM-Tg-mg-MP1543-Ab-1/ GM-Tg-mg-MP1543-Ab-2; GM-Tg-cynog-MP1543-Ab-1/ GM-Tg-cynog-MP1543-Ab-2;
GM-Tg-felg-MP1543-Ab-1/ GM-Tg-felg-MP1543-Ab-2; GM-Tg-cang-MP1543-Ab-1/ GM-Tg-cang-MP1543-Ab-2;
GM-Tg-bovg-MP1543-Ab-1/ GM-Tg-bovg-MP1543-Ab-2; GM-Tg-equg-MP1543-Ab-1/ GM-Tg-equg-MP1543-Ab-2
Products NameAnti-SLC16A12 monoclonal antibody
Formatmab
Target NameSLC16A12
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC16A12 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MOT12/ SLC16A12/ CJMG VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1543
    Target NameSLC16A12
    Gene ID387700,240638,309525,695916,486789,101083210,538469,100071573
    Gene Symbol and Synonyms3230401A21,CJMG,CRT2,CTRCT47,MCT 12,MCT12,RGD1311468,SLC16A12
    Uniprot AccessionQ6ZSM3,D4A734
    Uniprot Entry NameMOT12_HUMAN,MOT12_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000152779
    Target ClassificationN/A

    The target: SLC16A12, gene name: SLC16A12, also named as CJMG, CRT2, CTRCT47, MCT12. This gene encodes a transmembrane transporter that likely plays a role in monocarboxylic acid transport. A mutation in this gene has been associated with juvenile cataracts with microcornea and renal glucosuria. [provided by RefSeq, Mar 2010].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.