Anti-MOT2/ SLC16A7/ MCT2 monoclonal antibody

Anti-MOT2/ SLC16A7/ MCT2 antibody for FACS & in-vivo assay

Target products collectionGo to SLC16A7/SLC16A7 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1545-Ab-1/ GM-Tg-hg-MP1545-Ab-2Anti-Human SLC16A7 monoclonal antibodyHuman
GM-Tg-rg-MP1545-Ab-1/ GM-Tg-rg-MP1545-Ab-2Anti-Rat SLC16A7 monoclonal antibodyRat
GM-Tg-mg-MP1545-Ab-1/ GM-Tg-mg-MP1545-Ab-2Anti-Mouse SLC16A7 monoclonal antibodyMouse
GM-Tg-cynog-MP1545-Ab-1/ GM-Tg-cynog-MP1545-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC16A7 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1545-Ab-1/ GM-Tg-felg-MP1545-Ab-2Anti-Feline SLC16A7 monoclonal antibodyFeline
GM-Tg-cang-MP1545-Ab-1/ GM-Tg-cang-MP1545-Ab-2Anti-Canine SLC16A7 monoclonal antibodyCanine
GM-Tg-bovg-MP1545-Ab-1/ GM-Tg-bovg-MP1545-Ab-2Anti-Bovine SLC16A7 monoclonal antibodyBovine
GM-Tg-equg-MP1545-Ab-1/ GM-Tg-equg-MP1545-Ab-2Anti-Equine SLC16A7 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1545-Ab-1/ GM-Tg-hg-MP1545-Ab-2; GM-Tg-rg-MP1545-Ab-1/ GM-Tg-rg-MP1545-Ab-2;
GM-Tg-mg-MP1545-Ab-1/ GM-Tg-mg-MP1545-Ab-2; GM-Tg-cynog-MP1545-Ab-1/ GM-Tg-cynog-MP1545-Ab-2;
GM-Tg-felg-MP1545-Ab-1/ GM-Tg-felg-MP1545-Ab-2; GM-Tg-cang-MP1545-Ab-1/ GM-Tg-cang-MP1545-Ab-2;
GM-Tg-bovg-MP1545-Ab-1/ GM-Tg-bovg-MP1545-Ab-2; GM-Tg-equg-MP1545-Ab-1/ GM-Tg-equg-MP1545-Ab-2
Products NameAnti-SLC16A7 monoclonal antibody
Formatmab
Target NameSLC16A7
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC16A7 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MOT2/ SLC16A7/ MCT2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1545
    Target NameSLC16A7
    Gene ID9194,20503,29735,716540,481138,101084120,614573
    Gene Symbol and Synonyms4921534N07Rik,9030411M13Rik,D630004K10Rik,MCT2,SLC16A7
    Uniprot AccessionO60669,Q63344
    Uniprot Entry NameMOT2_HUMAN,MOT2_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000118596
    Target ClassificationN/A

    The target: SLC16A7, gene name: SLC16A7, also named as MCT2. This gene is a member of the monocarboxylate transporter family. Members in this family transport metabolites, such as lactate, pyruvate, and ketone bodies. The protein encoded by this gene catalyzes the proton-linked transport of monocarboxylates and has the highest affinity for pyruvate. This protein has been reported to be more highly expressed in prostate and colorectal cancer specimens when compared to control specimens. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.