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Anti-NPT4/ SLC17A3/ GOUT4 monoclonal antibody
Anti-NPT4/ SLC17A3/ GOUT4 antibody for FACS & in-vivo assay
Go to SLC17A3/SLC17A3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1549-Ab-1/ GM-Tg-hg-MP1549-Ab-2 | Anti-Human SLC17A3 monoclonal antibody | Human |
| GM-Tg-rg-MP1549-Ab-1/ GM-Tg-rg-MP1549-Ab-2 | Anti-Rat SLC17A3 monoclonal antibody | Rat |
| GM-Tg-mg-MP1549-Ab-1/ GM-Tg-mg-MP1549-Ab-2 | Anti-Mouse SLC17A3 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1549-Ab-1/ GM-Tg-cynog-MP1549-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC17A3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1549-Ab-1/ GM-Tg-felg-MP1549-Ab-2 | Anti-Feline SLC17A3 monoclonal antibody | Feline |
| GM-Tg-cang-MP1549-Ab-1/ GM-Tg-cang-MP1549-Ab-2 | Anti-Canine SLC17A3 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1549-Ab-1/ GM-Tg-bovg-MP1549-Ab-2 | Anti-Bovine SLC17A3 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1549-Ab-1/ GM-Tg-equg-MP1549-Ab-2 | Anti-Equine SLC17A3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1549-Ab-1/ GM-Tg-hg-MP1549-Ab-2; GM-Tg-rg-MP1549-Ab-1/ GM-Tg-rg-MP1549-Ab-2; GM-Tg-mg-MP1549-Ab-1/ GM-Tg-mg-MP1549-Ab-2; GM-Tg-cynog-MP1549-Ab-1/ GM-Tg-cynog-MP1549-Ab-2; GM-Tg-felg-MP1549-Ab-1/ GM-Tg-felg-MP1549-Ab-2; GM-Tg-cang-MP1549-Ab-1/ GM-Tg-cang-MP1549-Ab-2; GM-Tg-bovg-MP1549-Ab-1/ GM-Tg-bovg-MP1549-Ab-2; GM-Tg-equg-MP1549-Ab-1/ GM-Tg-equg-MP1549-Ab-2 |
| Products Name | Anti-SLC17A3 monoclonal antibody |
| Format | mab |
| Target Name | SLC17A3 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLC17A3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species NPT4/ SLC17A3/ GOUT4 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP001237 | human SLC17A3 Lentivirus plasmid |
| ORF Viral Vector | vGMLP001237 | human SLC17A3 Lentivirus particle |
| ORF Viral Vector | pGMLPm002080 | mouse Slc17a3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm002080 | mouse Slc17a3 Lentivirus particle |
Target information
| Target ID | GM-MP1549 |
| Target Name | SLC17A3 |
| Gene ID | 10786,105355,266730,695146,478741,101095655,519345,100052814 |
| Gene Symbol and Synonyms | GOUT4,NPT4,Rnpt4,SLC17A3,UAQTL4 |
| Uniprot Accession | O00476 |
| Uniprot Entry Name | NPT4_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000124564 |
| Target Classification | N/A |
The target: SLC17A3, gene name: SLC17A3, also named as GOUT4, NPT4, UAQTL4. The protein encoded by this gene is a voltage-driven transporter that excretes intracellular urate and organic anions from the blood into renal tubule cells. Two transcript variants encoding different isoforms have been found for this gene. The longer isoform is a plasma membrane protein with transporter activity while the shorter isoform localizes to the endoplasmic reticulum. [provided by RefSeq, Aug 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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