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Anti-S19A2/ SLC19A2/ TC1 monoclonal antibody
Anti-S19A2/ SLC19A2/ TC1 antibody for FACS & in-vivo assay
Go to SLC19A2/SLC19A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1551-Ab-1/ GM-Tg-hg-MP1551-Ab-2 | Anti-Human SLC19A2 monoclonal antibody | Human |
| GM-Tg-rg-MP1551-Ab-1/ GM-Tg-rg-MP1551-Ab-2 | Anti-Rat SLC19A2 monoclonal antibody | Rat |
| GM-Tg-mg-MP1551-Ab-1/ GM-Tg-mg-MP1551-Ab-2 | Anti-Mouse SLC19A2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1551-Ab-1/ GM-Tg-cynog-MP1551-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC19A2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1551-Ab-1/ GM-Tg-felg-MP1551-Ab-2 | Anti-Feline SLC19A2 monoclonal antibody | Feline |
| GM-Tg-cang-MP1551-Ab-1/ GM-Tg-cang-MP1551-Ab-2 | Anti-Canine SLC19A2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1551-Ab-1/ GM-Tg-bovg-MP1551-Ab-2 | Anti-Bovine SLC19A2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1551-Ab-1/ GM-Tg-equg-MP1551-Ab-2 | Anti-Equine SLC19A2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1551-Ab-1/ GM-Tg-hg-MP1551-Ab-2; GM-Tg-rg-MP1551-Ab-1/ GM-Tg-rg-MP1551-Ab-2; GM-Tg-mg-MP1551-Ab-1/ GM-Tg-mg-MP1551-Ab-2; GM-Tg-cynog-MP1551-Ab-1/ GM-Tg-cynog-MP1551-Ab-2; GM-Tg-felg-MP1551-Ab-1/ GM-Tg-felg-MP1551-Ab-2; GM-Tg-cang-MP1551-Ab-1/ GM-Tg-cang-MP1551-Ab-2; GM-Tg-bovg-MP1551-Ab-1/ GM-Tg-bovg-MP1551-Ab-2; GM-Tg-equg-MP1551-Ab-1/ GM-Tg-equg-MP1551-Ab-2 |
| Products Name | Anti-SLC19A2 monoclonal antibody |
| Format | mab |
| Target Name | SLC19A2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLC19A2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species S19A2/ SLC19A2/ TC1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP003771 | human SLC19A2 Lentivirus plasmid |
| ORF Viral Vector | vGMLP003771 | human SLC19A2 Lentivirus particle |
| ORF Viral Vector | pGMLPm005247 | mouse Slc19a2 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm005247 | mouse Slc19a2 Lentivirus particle |
Target information
| Target ID | GM-MP1551 |
| Target Name | SLC19A2 |
| Gene ID | 10560,116914,289175,700684,490353,664737,532860,100058457 |
| Gene Symbol and Synonyms | DDA1,SLC19A2,TC1,THMD1,THT1,ThTr-1,THTR1,TRMA |
| Uniprot Accession | O60779 |
| Uniprot Entry Name | S19A2_HUMAN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | Cancer |
| Gene Ensembl | ENSG00000117479 |
| Target Classification | Tumor-associated antigen (TAA) |
The target: SLC19A2, gene name: SLC19A2, also named as TC1, THMD1, THT1, THTR1, TRMA. This gene encodes the thiamin transporter protein. Mutations in this gene cause thiamin-responsive megaloblastic anemia syndrome (TRMA), which is an autosomal recessive disorder characterized by diabetes mellitus, megaloblastic anemia and sensorineural deafness. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
