Anti-S20A2/ SLC20A2/ GLVR-2 monoclonal antibody
Anti-S20A2/ SLC20A2/ GLVR-2 antibody for FACS & in-vivo assay
Go to SLC20A2/SLC20A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-MP1554-Ab-1/ GM-Tg-hg-MP1554-Ab-2 | Anti-Human SLC20A2 monoclonal antibody | Human |
GM-Tg-rg-MP1554-Ab-1/ GM-Tg-rg-MP1554-Ab-2 | Anti-Rat SLC20A2 monoclonal antibody | Rat |
GM-Tg-mg-MP1554-Ab-1/ GM-Tg-mg-MP1554-Ab-2 | Anti-Mouse SLC20A2 monoclonal antibody | Mouse |
GM-Tg-cynog-MP1554-Ab-1/ GM-Tg-cynog-MP1554-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC20A2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-MP1554-Ab-1/ GM-Tg-felg-MP1554-Ab-2 | Anti-Feline SLC20A2 monoclonal antibody | Feline |
GM-Tg-cang-MP1554-Ab-1/ GM-Tg-cang-MP1554-Ab-2 | Anti-Canine SLC20A2 monoclonal antibody | Canine |
GM-Tg-bovg-MP1554-Ab-1/ GM-Tg-bovg-MP1554-Ab-2 | Anti-Bovine SLC20A2 monoclonal antibody | Bovine |
GM-Tg-equg-MP1554-Ab-1/ GM-Tg-equg-MP1554-Ab-2 | Anti-Equine SLC20A2 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-MP1554-Ab-1/ GM-Tg-hg-MP1554-Ab-2; GM-Tg-rg-MP1554-Ab-1/ GM-Tg-rg-MP1554-Ab-2; GM-Tg-mg-MP1554-Ab-1/ GM-Tg-mg-MP1554-Ab-2; GM-Tg-cynog-MP1554-Ab-1/ GM-Tg-cynog-MP1554-Ab-2; GM-Tg-felg-MP1554-Ab-1/ GM-Tg-felg-MP1554-Ab-2; GM-Tg-cang-MP1554-Ab-1/ GM-Tg-cang-MP1554-Ab-2; GM-Tg-bovg-MP1554-Ab-1/ GM-Tg-bovg-MP1554-Ab-2; GM-Tg-equg-MP1554-Ab-1/ GM-Tg-equg-MP1554-Ab-2 |
Products Name | Anti-SLC20A2 monoclonal antibody |
Format | mab |
Target Name | SLC20A2 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-SLC20A2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species S20A2/ SLC20A2/ GLVR-2 VLP (virus-like particle) (Products Developing) |
Target information
Target ID | GM-MP1554 |
Target Name | SLC20A2 |
Gene ID | 6575,20516,29502,705242,482838,493788,518905,100054432 |
Gene Symbol and Synonyms | Ab1-188,GLVR-2,GLVR2,IBGC1,IBGC2,IBGC3,MLVAR,MolPit2,PIT-2,PIT2,Ram-1,RAM1,SLC20A2 |
Uniprot Accession | Q08357,Q63488,Q95L97,A1A4I1 |
Uniprot Entry Name | S20A2_HUMAN,S20A2_RAT,S20A2_FELCA,S20A2_BOVIN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000168575 |
Target Classification | N/A |
The target: SLC20A2, gene name: SLC20A2, also named as GLVR-2, GLVR2, IBGC1, IBGC3, MLVAR, PIT-2, PIT2, RAM1, Ram-1. This gene encodes a member of the inorganic phosphate transporter family. The encoded protein is a type 3 sodium-dependent phosphate symporter that plays an important role in phosphate homeostasis by mediating cellular phosphate uptake. The encoded protein also confers susceptibility to viral infection as a gamma-retroviral receptor. Mutations in this gene may play a role in familial idiopathic basal ganglia calcification. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.