Anti-NCKX1/ SLC24A1/ CSNB1D monoclonal antibody

Anti-NCKX1/ SLC24A1/ CSNB1D antibody for FACS & in-vivo assay

Target products collectionGo to SLC24A1/SLC24A1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1567-Ab-1/ GM-Tg-hg-MP1567-Ab-2Anti-Human SLC24A1 monoclonal antibodyHuman
GM-Tg-rg-MP1567-Ab-1/ GM-Tg-rg-MP1567-Ab-2Anti-Rat SLC24A1 monoclonal antibodyRat
GM-Tg-mg-MP1567-Ab-1/ GM-Tg-mg-MP1567-Ab-2Anti-Mouse SLC24A1 monoclonal antibodyMouse
GM-Tg-cynog-MP1567-Ab-1/ GM-Tg-cynog-MP1567-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC24A1 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1567-Ab-1/ GM-Tg-felg-MP1567-Ab-2Anti-Feline SLC24A1 monoclonal antibodyFeline
GM-Tg-cang-MP1567-Ab-1/ GM-Tg-cang-MP1567-Ab-2Anti-Canine SLC24A1 monoclonal antibodyCanine
GM-Tg-bovg-MP1567-Ab-1/ GM-Tg-bovg-MP1567-Ab-2Anti-Bovine SLC24A1 monoclonal antibodyBovine
GM-Tg-equg-MP1567-Ab-1/ GM-Tg-equg-MP1567-Ab-2Anti-Equine SLC24A1 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1567-Ab-1/ GM-Tg-hg-MP1567-Ab-2; GM-Tg-rg-MP1567-Ab-1/ GM-Tg-rg-MP1567-Ab-2;
GM-Tg-mg-MP1567-Ab-1/ GM-Tg-mg-MP1567-Ab-2; GM-Tg-cynog-MP1567-Ab-1/ GM-Tg-cynog-MP1567-Ab-2;
GM-Tg-felg-MP1567-Ab-1/ GM-Tg-felg-MP1567-Ab-2; GM-Tg-cang-MP1567-Ab-1/ GM-Tg-cang-MP1567-Ab-2;
GM-Tg-bovg-MP1567-Ab-1/ GM-Tg-bovg-MP1567-Ab-2; GM-Tg-equg-MP1567-Ab-1/ GM-Tg-equg-MP1567-Ab-2
Products NameAnti-SLC24A1 monoclonal antibody
Formatmab
Target NameSLC24A1
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC24A1 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species NCKX1/ SLC24A1/ CSNB1D VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1567
    Target NameSLC24A1
    Gene ID9187,214111,56814,713970,100683168,101082915,282474,100066201
    Gene Symbol and SynonymsCSNB1D,HsT17412,NCKX,NCKX1,RODX,SLC24A1
    Uniprot AccessionO60721,Q9QZM6,Q28139
    Uniprot Entry NameNCKX1_HUMAN,NCKX1_RAT,NCKX1_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000074621
    Target ClassificationN/A

    The target: SLC24A1, gene name: SLC24A1, also named as CSNB1D, HsT17412, NCKX, NCKX1, RODX. This gene encodes a member of the potassium-dependent sodium/calcium exchanger protein family. The encoded protein plays an important role in sodium/calcium exchange in retinal rod and cone photoreceptors by mediating the extrusion of one calcium ion and one potassium ion in exchange for four sodium ions. Mutations in this gene may play a role in congenital stationary night blindness. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.