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Anti-ADT4/ SLC25A31/ AAC4 monoclonal antibody
Anti-ADT4/ SLC25A31/ AAC4 antibody for FACS & in-vivo assay
Go to SLC25A31/SLC25A31 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1571-Ab-1/ GM-Tg-hg-MP1571-Ab-2 | Anti-Human SLC25A31 monoclonal antibody | Human |
| GM-Tg-rg-MP1571-Ab-1/ GM-Tg-rg-MP1571-Ab-2 | Anti-Rat SLC25A31 monoclonal antibody | Rat |
| GM-Tg-mg-MP1571-Ab-1/ GM-Tg-mg-MP1571-Ab-2 | Anti-Mouse SLC25A31 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1571-Ab-1/ GM-Tg-cynog-MP1571-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC25A31 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1571-Ab-1/ GM-Tg-felg-MP1571-Ab-2 | Anti-Feline SLC25A31 monoclonal antibody | Feline |
| GM-Tg-cang-MP1571-Ab-1/ GM-Tg-cang-MP1571-Ab-2 | Anti-Canine SLC25A31 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1571-Ab-1/ GM-Tg-bovg-MP1571-Ab-2 | Anti-Bovine SLC25A31 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1571-Ab-1/ GM-Tg-equg-MP1571-Ab-2 | Anti-Equine SLC25A31 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1571-Ab-1/ GM-Tg-hg-MP1571-Ab-2; GM-Tg-rg-MP1571-Ab-1/ GM-Tg-rg-MP1571-Ab-2; GM-Tg-mg-MP1571-Ab-1/ GM-Tg-mg-MP1571-Ab-2; GM-Tg-cynog-MP1571-Ab-1/ GM-Tg-cynog-MP1571-Ab-2; GM-Tg-felg-MP1571-Ab-1/ GM-Tg-felg-MP1571-Ab-2; GM-Tg-cang-MP1571-Ab-1/ GM-Tg-cang-MP1571-Ab-2; GM-Tg-bovg-MP1571-Ab-1/ GM-Tg-bovg-MP1571-Ab-2; GM-Tg-equg-MP1571-Ab-1/ GM-Tg-equg-MP1571-Ab-2 |
| Products Name | Anti-SLC25A31 monoclonal antibody |
| Format | mab |
| Target Name | SLC25A31 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLC25A31 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ADT4/ SLC25A31/ AAC4 VLP (virus-like particle) (Products Developing) |
Target information
| Target ID | GM-MP1571 |
| Target Name | SLC25A31 |
| Gene ID | 83447,73333,689108,710042,483832,101086294,541168,100071908 |
| Gene Symbol and Synonyms | 1700034J06Rik,AAC4,ANT 4,ANT4,Sfec,SFEC35kDa,SLC25A31 |
| Uniprot Accession | Q9H0C2,Q2YDD9 |
| Uniprot Entry Name | ADT4_HUMAN,ADT4_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000151475 |
| Target Classification | N/A |
The target: SLC25A31, gene name: SLC25A31, also named as AAC4, ANT 4, ANT4, SFEC35kDa. The protein encoded by this gene is a member of the ADP/ATP carrier family of proteins that exchange cytosolic ADP for matrix ATP in the mitochondria. Cells over-expressing this gene have been shown to display an anti-apoptotic phenotype. This protein is also thought to play a role in spermatogenesis, where it is believed to associate with a part of the flagellar cytoskeleton and with glycolytic enzymes. Male mice with mutations in the mouse ortholog of this gene are sterile and spermatocytes display an early meiotic arrest phenotype. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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