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Anti-S27A2/ SLC27A2/ ACSVL1 monoclonal antibody
Anti-S27A2/ SLC27A2/ ACSVL1 antibody for FACS & in-vivo assay
Go to SLC27A2/SLC27A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1582-Ab-1/ GM-Tg-hg-MP1582-Ab-2 | Anti-Human SLC27A2 monoclonal antibody | Human |
| GM-Tg-rg-MP1582-Ab-1/ GM-Tg-rg-MP1582-Ab-2 | Anti-Rat SLC27A2 monoclonal antibody | Rat |
| GM-Tg-mg-MP1582-Ab-1/ GM-Tg-mg-MP1582-Ab-2 | Anti-Mouse SLC27A2 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1582-Ab-1/ GM-Tg-cynog-MP1582-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC27A2 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1582-Ab-1/ GM-Tg-felg-MP1582-Ab-2 | Anti-Feline SLC27A2 monoclonal antibody | Feline |
| GM-Tg-cang-MP1582-Ab-1/ GM-Tg-cang-MP1582-Ab-2 | Anti-Canine SLC27A2 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1582-Ab-1/ GM-Tg-bovg-MP1582-Ab-2 | Anti-Bovine SLC27A2 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1582-Ab-1/ GM-Tg-equg-MP1582-Ab-2 | Anti-Equine SLC27A2 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1582-Ab-1/ GM-Tg-hg-MP1582-Ab-2; GM-Tg-rg-MP1582-Ab-1/ GM-Tg-rg-MP1582-Ab-2; GM-Tg-mg-MP1582-Ab-1/ GM-Tg-mg-MP1582-Ab-2; GM-Tg-cynog-MP1582-Ab-1/ GM-Tg-cynog-MP1582-Ab-2; GM-Tg-felg-MP1582-Ab-1/ GM-Tg-felg-MP1582-Ab-2; GM-Tg-cang-MP1582-Ab-1/ GM-Tg-cang-MP1582-Ab-2; GM-Tg-bovg-MP1582-Ab-1/ GM-Tg-bovg-MP1582-Ab-2; GM-Tg-equg-MP1582-Ab-1/ GM-Tg-equg-MP1582-Ab-2 |
| Products Name | Anti-SLC27A2 monoclonal antibody |
| Format | mab |
| Target Name | SLC27A2 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLC27A2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species S27A2/ SLC27A2/ ACSVL1 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP003244 | human SLC27A2 Lentivirus particle |
| ORF Viral Vector | pGMLP003244 | human SLC27A2 Lentivirus plasmid |
Target information
| Target ID | GM-MP1582 |
| Target Name | SLC27A2 |
| Gene ID | 11001,26458,65192,715237,478298,101096897,535727,100069953 |
| Gene Symbol and Synonyms | ACSVL1,FACVL1,FATP2,hFACVL1,HsT17226,SLC27A2,Vlac,VLACS,VLCS |
| Uniprot Accession | O14975,P97524 |
| Uniprot Entry Name | S27A2_HUMAN,S27A2_RAT |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000140284 |
| Target Classification | N/A |
The target: SLC27A2, gene name: SLC27A2, also named as ACSVL1, FACVL1, FATP2, HsT17226, VLACS, VLCS, hFACVL1. The protein encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes, but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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