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Anti-S29A3/ SLC29A3/ ENT3 monoclonal antibody
Anti-S29A3/ SLC29A3/ ENT3 antibody for FACS & in-vivo assay
Go to SLC29A3/SLC29A3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1587-Ab-1/ GM-Tg-hg-MP1587-Ab-2 | Anti-Human SLC29A3 monoclonal antibody | Human |
| GM-Tg-rg-MP1587-Ab-1/ GM-Tg-rg-MP1587-Ab-2 | Anti-Rat SLC29A3 monoclonal antibody | Rat |
| GM-Tg-mg-MP1587-Ab-1/ GM-Tg-mg-MP1587-Ab-2 | Anti-Mouse SLC29A3 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1587-Ab-1/ GM-Tg-cynog-MP1587-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC29A3 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1587-Ab-1/ GM-Tg-felg-MP1587-Ab-2 | Anti-Feline SLC29A3 monoclonal antibody | Feline |
| GM-Tg-cang-MP1587-Ab-1/ GM-Tg-cang-MP1587-Ab-2 | Anti-Canine SLC29A3 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1587-Ab-1/ GM-Tg-bovg-MP1587-Ab-2 | Anti-Bovine SLC29A3 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1587-Ab-1/ GM-Tg-equg-MP1587-Ab-2 | Anti-Equine SLC29A3 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1587-Ab-1/ GM-Tg-hg-MP1587-Ab-2; GM-Tg-rg-MP1587-Ab-1/ GM-Tg-rg-MP1587-Ab-2; GM-Tg-mg-MP1587-Ab-1/ GM-Tg-mg-MP1587-Ab-2; GM-Tg-cynog-MP1587-Ab-1/ GM-Tg-cynog-MP1587-Ab-2; GM-Tg-felg-MP1587-Ab-1/ GM-Tg-felg-MP1587-Ab-2; GM-Tg-cang-MP1587-Ab-1/ GM-Tg-cang-MP1587-Ab-2; GM-Tg-bovg-MP1587-Ab-1/ GM-Tg-bovg-MP1587-Ab-2; GM-Tg-equg-MP1587-Ab-1/ GM-Tg-equg-MP1587-Ab-2 |
| Products Name | Anti-SLC29A3 monoclonal antibody |
| Format | mab |
| Target Name | SLC29A3 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLC29A3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species S29A3/ SLC29A3/ ENT3 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLPm004406 | mouse Slc29a3 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm004406 | mouse Slc29a3 Lentivirus particle |
Target information
| Target ID | GM-MP1587 |
| Target Name | SLC29A3 |
| Gene ID | 55315,71279,353307,709682,489034,101097175,504503,100072768 |
| Gene Symbol and Synonyms | 4933435C21Rik,ENT3,HCLAP,HJCD,PHID,SLC29A3 |
| Uniprot Accession | Q9BZD2,Q80WK7,A1A4N1 |
| Uniprot Entry Name | S29A3_HUMAN,S29A3_RAT,S29A3_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000198246 |
| Target Classification | N/A |
The target: SLC29A3, gene name: SLC29A3, also named as ENT3, HCLAP, HJCD, PHID. This gene encodes a nucleoside transporter. The encoded protein plays a role in cellular uptake of nucleosides, nucleobases, and their related analogs. Mutations in this gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism. A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus. Alternatively spliced transcript variants have been described.[provided by RefSeq, Mar 2010].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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