Anti-MYCT/ SLC2A13/ HMIT monoclonal antibody

Anti-MYCT/ SLC2A13/ HMIT antibody for FACS & in-vivo assay

Target products collectionGo to SLC2A13/SLC2A13 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1590-Ab-1/ GM-Tg-hg-MP1590-Ab-2Anti-Human SLC2A13 monoclonal antibodyHuman
GM-Tg-rg-MP1590-Ab-1/ GM-Tg-rg-MP1590-Ab-2Anti-Rat SLC2A13 monoclonal antibodyRat
GM-Tg-mg-MP1590-Ab-1/ GM-Tg-mg-MP1590-Ab-2Anti-Mouse SLC2A13 monoclonal antibodyMouse
GM-Tg-cynog-MP1590-Ab-1/ GM-Tg-cynog-MP1590-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC2A13 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1590-Ab-1/ GM-Tg-felg-MP1590-Ab-2Anti-Feline SLC2A13 monoclonal antibodyFeline
GM-Tg-cang-MP1590-Ab-1/ GM-Tg-cang-MP1590-Ab-2Anti-Canine SLC2A13 monoclonal antibodyCanine
GM-Tg-bovg-MP1590-Ab-1/ GM-Tg-bovg-MP1590-Ab-2Anti-Bovine SLC2A13 monoclonal antibodyBovine
GM-Tg-equg-MP1590-Ab-1/ GM-Tg-equg-MP1590-Ab-2Anti-Equine SLC2A13 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1590-Ab-1/ GM-Tg-hg-MP1590-Ab-2; GM-Tg-rg-MP1590-Ab-1/ GM-Tg-rg-MP1590-Ab-2;
GM-Tg-mg-MP1590-Ab-1/ GM-Tg-mg-MP1590-Ab-2; GM-Tg-cynog-MP1590-Ab-1/ GM-Tg-cynog-MP1590-Ab-2;
GM-Tg-felg-MP1590-Ab-1/ GM-Tg-felg-MP1590-Ab-2; GM-Tg-cang-MP1590-Ab-1/ GM-Tg-cang-MP1590-Ab-2;
GM-Tg-bovg-MP1590-Ab-1/ GM-Tg-bovg-MP1590-Ab-2; GM-Tg-equg-MP1590-Ab-1/ GM-Tg-equg-MP1590-Ab-2
Products NameAnti-SLC2A13 monoclonal antibody
Formatmab
Target NameSLC2A13
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC2A13 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species MYCT/ SLC2A13/ HMIT VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1590
    Target NameSLC2A13
    Gene ID114134,239606,171147,697822,486609,101095907,613556,100146160
    Gene Symbol and Synonyms6530403A04,A630029G22Rik,Gm308,HMIT,SLC2A13
    Uniprot AccessionQ96QE2,Q921A2
    Uniprot Entry NameMYCT_HUMAN,MYCT_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000151229
    Target ClassificationN/A

    The target: SLC2A13, gene name: SLC2A13, also named as HMIT. Enables ATPase binding activity; myo-inositol:proton symporter activity; and protease binding activity. Involved in myo-inositol transport and positive regulation of amyloid-beta formation. Is integral component of plasma membrane. Part of cell body; cell periphery; and cell projection. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.