Anti-GTR3/ SLC2A3/ GLUT3 monoclonal antibody

Anti-GTR3/ SLC2A3/ GLUT3 antibody for FACS & in-vivo assay

Target products collectionGo to SLC2A3/SLC2A3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1593-Ab-1/ GM-Tg-hg-MP1593-Ab-2Anti-Human SLC2A3 monoclonal antibodyHuman
GM-Tg-rg-MP1593-Ab-1/ GM-Tg-rg-MP1593-Ab-2Anti-Rat SLC2A3 monoclonal antibodyRat
GM-Tg-mg-MP1593-Ab-1/ GM-Tg-mg-MP1593-Ab-2Anti-Mouse SLC2A3 monoclonal antibodyMouse
GM-Tg-cynog-MP1593-Ab-1/ GM-Tg-cynog-MP1593-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC2A3 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1593-Ab-1/ GM-Tg-felg-MP1593-Ab-2Anti-Feline SLC2A3 monoclonal antibodyFeline
GM-Tg-cang-MP1593-Ab-1/ GM-Tg-cang-MP1593-Ab-2Anti-Canine SLC2A3 monoclonal antibodyCanine
GM-Tg-bovg-MP1593-Ab-1/ GM-Tg-bovg-MP1593-Ab-2Anti-Bovine SLC2A3 monoclonal antibodyBovine
GM-Tg-equg-MP1593-Ab-1/ GM-Tg-equg-MP1593-Ab-2Anti-Equine SLC2A3 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1593-Ab-1/ GM-Tg-hg-MP1593-Ab-2; GM-Tg-rg-MP1593-Ab-1/ GM-Tg-rg-MP1593-Ab-2;
GM-Tg-mg-MP1593-Ab-1/ GM-Tg-mg-MP1593-Ab-2; GM-Tg-cynog-MP1593-Ab-1/ GM-Tg-cynog-MP1593-Ab-2;
GM-Tg-felg-MP1593-Ab-1/ GM-Tg-felg-MP1593-Ab-2; GM-Tg-cang-MP1593-Ab-1/ GM-Tg-cang-MP1593-Ab-2;
GM-Tg-bovg-MP1593-Ab-1/ GM-Tg-bovg-MP1593-Ab-2; GM-Tg-equg-MP1593-Ab-1/ GM-Tg-equg-MP1593-Ab-2
Products NameAnti-SLC2A3 monoclonal antibody
Formatmab
Target NameSLC2A3
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC2A3 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GTR3/ SLC2A3/ GLUT3 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorvGMLP003017human SLC2A3 Lentivirus particle
    ORF Viral VectorpGMLP003017human SLC2A3 Lentivirus plasmid
    ORF Viral VectorpGMLPm002971mouse Slc2a3 Lentivirus plasmid
    ORF Viral VectorvGMLPm002971mouse Slc2a3 Lentivirus particle


    Target information

    Target IDGM-MP1593
    Target NameSLC2A3
    Gene ID6515,20527,25551,403997,101096740,282358,100053371
    Gene Symbol and SynonymsGlut-3,GLUT3,SLC2A3
    Uniprot AccessionP11169,Q07647,P47842,P58352
    Uniprot Entry NameGTR3_HUMAN,GTR3_RAT,GTR3_CANLF,GTR3_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseBreast Cancer, Prostate Cancer
    Gene EnsemblENSG00000059804
    Target ClassificationN/A

    The target: SLC2A3, gene name: SLC2A3, also named as GLUT3. Enables dehydroascorbic acid transmembrane transporter activity; glucose binding activity; and glucose transmembrane transporter activity. Involved in glucose import across plasma membrane and transport across blood-brain barrier. Is integral component of plasma membrane. Biomarker of Alzheimer's disease; acanthosis nigricans; diabetes mellitus; and type 2 diabetes mellitus. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.