Anti-GTR5/ SLC2A5/ GLUT-5 monoclonal antibody

Anti-GTR5/ SLC2A5/ GLUT-5 antibody for FACS & in-vivo assay

Target products collectionGo to SLC2A5/SLC2A5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1594-Ab-1/ GM-Tg-hg-MP1594-Ab-2Anti-Human SLC2A5 monoclonal antibodyHuman
GM-Tg-rg-MP1594-Ab-1/ GM-Tg-rg-MP1594-Ab-2Anti-Rat SLC2A5 monoclonal antibodyRat
GM-Tg-mg-MP1594-Ab-1/ GM-Tg-mg-MP1594-Ab-2Anti-Mouse SLC2A5 monoclonal antibodyMouse
GM-Tg-cynog-MP1594-Ab-1/ GM-Tg-cynog-MP1594-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC2A5 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1594-Ab-1/ GM-Tg-felg-MP1594-Ab-2Anti-Feline SLC2A5 monoclonal antibodyFeline
GM-Tg-cang-MP1594-Ab-1/ GM-Tg-cang-MP1594-Ab-2Anti-Canine SLC2A5 monoclonal antibodyCanine
GM-Tg-bovg-MP1594-Ab-1/ GM-Tg-bovg-MP1594-Ab-2Anti-Bovine SLC2A5 monoclonal antibodyBovine
GM-Tg-equg-MP1594-Ab-1/ GM-Tg-equg-MP1594-Ab-2Anti-Equine SLC2A5 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1594-Ab-1/ GM-Tg-hg-MP1594-Ab-2; GM-Tg-rg-MP1594-Ab-1/ GM-Tg-rg-MP1594-Ab-2;
GM-Tg-mg-MP1594-Ab-1/ GM-Tg-mg-MP1594-Ab-2; GM-Tg-cynog-MP1594-Ab-1/ GM-Tg-cynog-MP1594-Ab-2;
GM-Tg-felg-MP1594-Ab-1/ GM-Tg-felg-MP1594-Ab-2; GM-Tg-cang-MP1594-Ab-1/ GM-Tg-cang-MP1594-Ab-2;
GM-Tg-bovg-MP1594-Ab-1/ GM-Tg-bovg-MP1594-Ab-2; GM-Tg-equg-MP1594-Ab-1/ GM-Tg-equg-MP1594-Ab-2
Products NameAnti-SLC2A5 monoclonal antibody
Formatmab
Target NameSLC2A5
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC2A5 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species GTR5/ SLC2A5/ GLUT-5 VLP (virus-like particle) (Products Developing)
    ORF Viral VectorpGMLP003129human SLC2A5 Lentivirus plasmid
    ORF Viral VectorvGMLP003129human SLC2A5 Lentivirus particle
    ORF Viral VectorpGMLPm002759mouse Slc2a5 Lentivirus plasmid
    ORF Viral VectorvGMLPm002759mouse Slc2a5 Lentivirus particle


    Target information

    Target IDGM-MP1594
    Target NameSLC2A5
    Gene ID6518,56485,65197,722154
    Gene Symbol and SynonymsGLUT-5,GLUT5,SLC2A5,Slc5a
    Uniprot AccessionP22732,P43427
    Uniprot Entry NameGTR5_HUMAN,GTR5_RAT
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000142583
    Target ClassificationN/A

    The target: SLC2A5, gene name: SLC2A5, also named as GLUT-5, GLUT5. The protein encoded by this gene is a fructose transporter responsible for fructose uptake by the small intestine. The encoded protein also is necessary for the increase in blood pressure due to high dietary fructose consumption. [provided by RefSeq, Jun 2016].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.