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Anti-GTR8/ SLC2A8/ GLUT8 monoclonal antibody
Anti-GTR8/ SLC2A8/ GLUT8 antibody for FACS & in-vivo assay
Go to SLC2A8/SLC2A8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1597-Ab-1/ GM-Tg-hg-MP1597-Ab-2 | Anti-Human SLC2A8 monoclonal antibody | Human |
| GM-Tg-rg-MP1597-Ab-1/ GM-Tg-rg-MP1597-Ab-2 | Anti-Rat SLC2A8 monoclonal antibody | Rat |
| GM-Tg-mg-MP1597-Ab-1/ GM-Tg-mg-MP1597-Ab-2 | Anti-Mouse SLC2A8 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1597-Ab-1/ GM-Tg-cynog-MP1597-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC2A8 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1597-Ab-1/ GM-Tg-felg-MP1597-Ab-2 | Anti-Feline SLC2A8 monoclonal antibody | Feline |
| GM-Tg-cang-MP1597-Ab-1/ GM-Tg-cang-MP1597-Ab-2 | Anti-Canine SLC2A8 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1597-Ab-1/ GM-Tg-bovg-MP1597-Ab-2 | Anti-Bovine SLC2A8 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1597-Ab-1/ GM-Tg-equg-MP1597-Ab-2 | Anti-Equine SLC2A8 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1597-Ab-1/ GM-Tg-hg-MP1597-Ab-2; GM-Tg-rg-MP1597-Ab-1/ GM-Tg-rg-MP1597-Ab-2; GM-Tg-mg-MP1597-Ab-1/ GM-Tg-mg-MP1597-Ab-2; GM-Tg-cynog-MP1597-Ab-1/ GM-Tg-cynog-MP1597-Ab-2; GM-Tg-felg-MP1597-Ab-1/ GM-Tg-felg-MP1597-Ab-2; GM-Tg-cang-MP1597-Ab-1/ GM-Tg-cang-MP1597-Ab-2; GM-Tg-bovg-MP1597-Ab-1/ GM-Tg-bovg-MP1597-Ab-2; GM-Tg-equg-MP1597-Ab-1/ GM-Tg-equg-MP1597-Ab-2 |
| Products Name | Anti-SLC2A8 monoclonal antibody |
| Format | mab |
| Target Name | SLC2A8 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLC2A8 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species GTR8/ SLC2A8/ GLUT8 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | vGMLP001574 | human SLC2A8 Lentivirus particle |
| ORF Viral Vector | pGMLP001574 | human SLC2A8 Lentivirus plasmid |
| ORF Viral Vector | pGMLPm005135 | mouse Slc2a8 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm005135 | mouse Slc2a8 Lentivirus particle |
Target information
| Target ID | GM-MP1597 |
| Target Name | SLC2A8 |
| Gene ID | 29988,56017,85256,701073,480717,101096270,282867,100070552 |
| Gene Symbol and Synonyms | D2Ertd44e,GLUT8,GLUTX1,SLC2A8 |
| Uniprot Accession | Q9NY64,Q9JJZ1,P58354 |
| Uniprot Entry Name | GTR8_HUMAN,GTR8_RAT,GTR8_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000136856 |
| Target Classification | N/A |
The target: SLC2A8, gene name: SLC2A8, also named as GLUT8, GLUTX1. This gene belongs to the solute carrier 2A family, which includes intracellular glucose transporters. Based on sequence comparison, the glucose transporters are grouped into three classes and this gene is a member of class II. The encoded protein, like other members of the family, contains several conserved residues and motifs and 12 transmembrane domains with both amino and carboxyl ends being on the cytosolic side of the membrane. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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