Anti-ZNT10/ SLC30A10/ HMDPC monoclonal antibody
Anti-ZNT10/ SLC30A10/ HMDPC antibody for FACS & in-vivo assay
Go to SLC30A10/SLC30A10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-MP1598-Ab-1/ GM-Tg-hg-MP1598-Ab-2 | Anti-Human SLC30A10 monoclonal antibody | Human |
GM-Tg-rg-MP1598-Ab-1/ GM-Tg-rg-MP1598-Ab-2 | Anti-Rat SLC30A10 monoclonal antibody | Rat |
GM-Tg-mg-MP1598-Ab-1/ GM-Tg-mg-MP1598-Ab-2 | Anti-Mouse SLC30A10 monoclonal antibody | Mouse |
GM-Tg-cynog-MP1598-Ab-1/ GM-Tg-cynog-MP1598-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC30A10 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-MP1598-Ab-1/ GM-Tg-felg-MP1598-Ab-2 | Anti-Feline SLC30A10 monoclonal antibody | Feline |
GM-Tg-cang-MP1598-Ab-1/ GM-Tg-cang-MP1598-Ab-2 | Anti-Canine SLC30A10 monoclonal antibody | Canine |
GM-Tg-bovg-MP1598-Ab-1/ GM-Tg-bovg-MP1598-Ab-2 | Anti-Bovine SLC30A10 monoclonal antibody | Bovine |
GM-Tg-equg-MP1598-Ab-1/ GM-Tg-equg-MP1598-Ab-2 | Anti-Equine SLC30A10 monoclonal antibody | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. | GM-Tg-hg-MP1598-Ab-1/ GM-Tg-hg-MP1598-Ab-2; GM-Tg-rg-MP1598-Ab-1/ GM-Tg-rg-MP1598-Ab-2; GM-Tg-mg-MP1598-Ab-1/ GM-Tg-mg-MP1598-Ab-2; GM-Tg-cynog-MP1598-Ab-1/ GM-Tg-cynog-MP1598-Ab-2; GM-Tg-felg-MP1598-Ab-1/ GM-Tg-felg-MP1598-Ab-2; GM-Tg-cang-MP1598-Ab-1/ GM-Tg-cang-MP1598-Ab-2; GM-Tg-bovg-MP1598-Ab-1/ GM-Tg-bovg-MP1598-Ab-2; GM-Tg-equg-MP1598-Ab-1/ GM-Tg-equg-MP1598-Ab-2 |
Products Name | Anti-SLC30A10 monoclonal antibody |
Format | mab |
Target Name | SLC30A10 |
Protein Sub-location | Transmembrane Protein |
Category of antibody | FACS/Biofunctional Antibody |
Derivation (species) | Mouse |
CH1+2+3 Isotype (Receptor identification) | IgG |
Type of Light Chain (VD-LC) | N/A |
Expression platform | Mammalian Expression |
Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
Tag | Fc |
Products description | Pre-made anti-SLC30A10 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation | Lyophilized from sterile PBS, PH 7.4 |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
Category | Cat No. | Products Name |
Target Antigen | Products Developing | Multi-species ZNT10/ SLC30A10/ HMDPC VLP (virus-like particle) (Products Developing) |
ORF Viral Vector | vGMAD000293 | human SLC30A10 Adenovirus particle |
ORF Viral Vector | pGMAAV000072 | human SLC30A10 AAV plasmid |
ORF Viral Vector | pGMAD000293 | human SLC30A10 Adenovirus plasmid |
ORF Viral Vector | vGMAAV000072 | human SLC30A10 AAV particle |
ORF Viral Vector | pGMLPm004937 | mouse Slc30a10 Lentivirus plasmid |
ORF Viral Vector | vGMLPm004937 | mouse Slc30a10 Lentivirus particle |
Target information
Target ID | GM-MP1598 |
Target Name | SLC30A10 |
Gene ID | 55532,226781,289353,706999,488599,101095711,508385,100050310 |
Gene Symbol and Synonyms | E130106K10Rik,Gm212,HMDPC,HMNDYT1,RGD1305098,SLC30A10,ZnT-10,ZNT10,ZNT8,ZRC1 |
Uniprot Accession | Q6XR72 |
Uniprot Entry Name | ZNT10_HUMAN |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000196660 |
Target Classification | N/A |
The target: SLC30A10, gene name: SLC30A10, also named as HMDPC, HMNDYT1, ZNT10, ZNT8, ZRC1, ZnT-10. This gene is highly expressed in the liver and is inducible by manganese. Its protein product appears to be critical in maintaining manganese levels, and has higher specificity for manganese than zinc. Loss of function mutations appear to result in a pleomorphic phenotype, including dystonia and adult-onset parkinsonism. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.