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Anti-ZNT4/ SLC30A4/ znT-4 monoclonal antibody
Anti-ZNT4/ SLC30A4/ znT-4 antibody for FACS & in-vivo assay
Go to SLC30A4/SLC30A4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)
MSDSProduct information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-MP1602-Ab-1/ GM-Tg-hg-MP1602-Ab-2 | Anti-Human SLC30A4 monoclonal antibody | Human |
| GM-Tg-rg-MP1602-Ab-1/ GM-Tg-rg-MP1602-Ab-2 | Anti-Rat SLC30A4 monoclonal antibody | Rat |
| GM-Tg-mg-MP1602-Ab-1/ GM-Tg-mg-MP1602-Ab-2 | Anti-Mouse SLC30A4 monoclonal antibody | Mouse |
| GM-Tg-cynog-MP1602-Ab-1/ GM-Tg-cynog-MP1602-Ab-2 | Anti-Cynomolgus/ Rhesus macaque SLC30A4 monoclonal antibody | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-MP1602-Ab-1/ GM-Tg-felg-MP1602-Ab-2 | Anti-Feline SLC30A4 monoclonal antibody | Feline |
| GM-Tg-cang-MP1602-Ab-1/ GM-Tg-cang-MP1602-Ab-2 | Anti-Canine SLC30A4 monoclonal antibody | Canine |
| GM-Tg-bovg-MP1602-Ab-1/ GM-Tg-bovg-MP1602-Ab-2 | Anti-Bovine SLC30A4 monoclonal antibody | Bovine |
| GM-Tg-equg-MP1602-Ab-1/ GM-Tg-equg-MP1602-Ab-2 | Anti-Equine SLC30A4 monoclonal antibody | Equine |
Size： 1mg | 10mg | 100mg
Product Description
| Catalog No. | GM-Tg-hg-MP1602-Ab-1/ GM-Tg-hg-MP1602-Ab-2; GM-Tg-rg-MP1602-Ab-1/ GM-Tg-rg-MP1602-Ab-2; GM-Tg-mg-MP1602-Ab-1/ GM-Tg-mg-MP1602-Ab-2; GM-Tg-cynog-MP1602-Ab-1/ GM-Tg-cynog-MP1602-Ab-2; GM-Tg-felg-MP1602-Ab-1/ GM-Tg-felg-MP1602-Ab-2; GM-Tg-cang-MP1602-Ab-1/ GM-Tg-cang-MP1602-Ab-2; GM-Tg-bovg-MP1602-Ab-1/ GM-Tg-bovg-MP1602-Ab-2; GM-Tg-equg-MP1602-Ab-1/ GM-Tg-equg-MP1602-Ab-2 |
| Products Name | Anti-SLC30A4 monoclonal antibody |
| Format | mab |
| Target Name | SLC30A4 |
| Protein Sub-location | Transmembrane Protein |
| Category of antibody | FACS/Biofunctional Antibody |
| Derivation (species) | Mouse |
| CH1+2+3 Isotype (Receptor identification) | IgG |
| Type of Light Chain (VD-LC) | N/A |
| Expression platform | Mammalian Expression |
| Bioactivity validation | Binding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD). |
| Tag | Fc |
| Products description | Pre-made anti-SLC30A4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Data / case study
Click to get more Data / Case study about the product.
Associated products
| Category | Cat No. | Products Name |
| Target Antigen | Products Developing | Multi-species ZNT4/ SLC30A4/ znT-4 VLP (virus-like particle) (Products Developing) |
| ORF Viral Vector | pGMLP000621 | human SLC30A4 Lentivirus plasmid |
| ORF Viral Vector | vGMLP000621 | human SLC30A4 Lentivirus particle |
| ORF Viral Vector | pGMLPm001708 | mouse Slc30a4 Lentivirus plasmid |
| ORF Viral Vector | vGMLPm001708 | mouse Slc30a4 Lentivirus particle |
Target information
| Target ID | GM-MP1602 |
| Target Name | SLC30A4 |
| Gene ID | 7782,22785,64469,713510,487539,101090112,540869,100055954 |
| Gene Symbol and Synonyms | lm,SLC30A4,znT-4,ZNT4 |
| Uniprot Accession | O14863,O55174,Q9TTF3 |
| Uniprot Entry Name | ZNT4_HUMAN,ZNT4_RAT,ZNT4_BOVIN |
| Protein Sub-location | Transmembrane Protein |
| Category | |
| Disease | N/A |
| Gene Ensembl | ENSG00000104154 |
| Target Classification | N/A |
The target: SLC30A4, gene name: SLC30A4, also named as ZNT4, znT-4. Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997 [PubMed 9354792]).[supplied by OMIM, Mar 2008].
About Gmab
GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.
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