Anti-COPT2/ SLC31A2/ CTR2 monoclonal antibody

Anti-COPT2/ SLC31A2/ CTR2 antibody for FACS & in-vivo assay

Target products collectionGo to SLC31A2/SLC31A2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1604-Ab-1/ GM-Tg-hg-MP1604-Ab-2Anti-Human SLC31A2 monoclonal antibodyHuman
GM-Tg-rg-MP1604-Ab-1/ GM-Tg-rg-MP1604-Ab-2Anti-Rat SLC31A2 monoclonal antibodyRat
GM-Tg-mg-MP1604-Ab-1/ GM-Tg-mg-MP1604-Ab-2Anti-Mouse SLC31A2 monoclonal antibodyMouse
GM-Tg-cynog-MP1604-Ab-1/ GM-Tg-cynog-MP1604-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC31A2 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1604-Ab-1/ GM-Tg-felg-MP1604-Ab-2Anti-Feline SLC31A2 monoclonal antibodyFeline
GM-Tg-cang-MP1604-Ab-1/ GM-Tg-cang-MP1604-Ab-2Anti-Canine SLC31A2 monoclonal antibodyCanine
GM-Tg-bovg-MP1604-Ab-1/ GM-Tg-bovg-MP1604-Ab-2Anti-Bovine SLC31A2 monoclonal antibodyBovine
GM-Tg-equg-MP1604-Ab-1/ GM-Tg-equg-MP1604-Ab-2Anti-Equine SLC31A2 monoclonal antibodyEquine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1604-Ab-1/ GM-Tg-hg-MP1604-Ab-2; GM-Tg-rg-MP1604-Ab-1/ GM-Tg-rg-MP1604-Ab-2;
GM-Tg-mg-MP1604-Ab-1/ GM-Tg-mg-MP1604-Ab-2; GM-Tg-cynog-MP1604-Ab-1/ GM-Tg-cynog-MP1604-Ab-2;
GM-Tg-felg-MP1604-Ab-1/ GM-Tg-felg-MP1604-Ab-2; GM-Tg-cang-MP1604-Ab-1/ GM-Tg-cang-MP1604-Ab-2;
GM-Tg-bovg-MP1604-Ab-1/ GM-Tg-bovg-MP1604-Ab-2; GM-Tg-equg-MP1604-Ab-1/ GM-Tg-equg-MP1604-Ab-2
Products NameAnti-SLC31A2 monoclonal antibody
Formatmab
Target NameSLC31A2
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)
IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC31A2 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species COPT2/ SLC31A2/ CTR2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1604
    Target NameSLC31A2
    Gene ID1318,20530,298091,706385,612526,101081337,526609,100053455
    Gene Symbol and SynonymsCOPT2,CTR2,hCTR2,SLC31A2
    Uniprot AccessionO15432
    Uniprot Entry NameCOPT2_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000136867
    Target ClassificationN/A

    The target: SLC31A2, gene name: SLC31A2, also named as COPT2, CTR2, hCTR2. Predicted to enable copper ion transmembrane transporter activity. Predicted to be involved in cellular copper ion homeostasis. Predicted to act upstream of or within regulation of copper ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.