Anti-S36A4/ SLC36A4/ PAT4 monoclonal antibody

Anti-S36A4/ SLC36A4/ PAT4 antibody for FACS & in-vivo assay

Target products collectionGo to SLC36A4/SLC36A4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1610-Ab-1/ GM-Tg-hg-MP1610-Ab-2Anti-Human SLC36A4 monoclonal antibodyHuman
GM-Tg-rg-MP1610-Ab-1/ GM-Tg-rg-MP1610-Ab-2Anti-Rat SLC36A4 monoclonal antibodyRat
GM-Tg-mg-MP1610-Ab-1/ GM-Tg-mg-MP1610-Ab-2Anti-Mouse SLC36A4 monoclonal antibodyMouse
GM-Tg-cynog-MP1610-Ab-1/ GM-Tg-cynog-MP1610-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC36A4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1610-Ab-1/ GM-Tg-felg-MP1610-Ab-2Anti-Feline SLC36A4 monoclonal antibodyFeline
GM-Tg-cang-MP1610-Ab-1/ GM-Tg-cang-MP1610-Ab-2Anti-Canine SLC36A4 monoclonal antibodyCanine
GM-Tg-bovg-MP1610-Ab-1/ GM-Tg-bovg-MP1610-Ab-2Anti-Bovine SLC36A4 monoclonal antibodyBovine
GM-Tg-equg-MP1610-Ab-1/ GM-Tg-equg-MP1610-Ab-2Anti-Equine SLC36A4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1610-Ab-1/ GM-Tg-hg-MP1610-Ab-2; GM-Tg-rg-MP1610-Ab-1/ GM-Tg-rg-MP1610-Ab-2;
GM-Tg-mg-MP1610-Ab-1/ GM-Tg-mg-MP1610-Ab-2; GM-Tg-cynog-MP1610-Ab-1/ GM-Tg-cynog-MP1610-Ab-2;
GM-Tg-felg-MP1610-Ab-1/ GM-Tg-felg-MP1610-Ab-2; GM-Tg-cang-MP1610-Ab-1/ GM-Tg-cang-MP1610-Ab-2;
GM-Tg-bovg-MP1610-Ab-1/ GM-Tg-bovg-MP1610-Ab-2; GM-Tg-equg-MP1610-Ab-1/ GM-Tg-equg-MP1610-Ab-2
Products NameAnti-SLC36A4 monoclonal antibody
Formatmab
Target NameSLC36A4
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC36A4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species S36A4/ SLC36A4/ PAT4 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1610
    Target NameSLC36A4
    Gene ID120103,234967,315439,696671,607790,101088185,616864,100059092
    Gene Symbol and Synonyms6330573I15Rik,PAT4,SLC36A4
    Uniprot AccessionQ6YBV0
    Uniprot Entry NameS36A4_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000180773
    Target ClassificationN/A

    The target: SLC36A4, gene name: SLC36A4, also named as PAT4. SLC36A4 belongs to the SLC36 family of amino acid transporters based on sequence similarity with other family members (e.g., SLC36A1; MIM 606561). SLC36 proteins contain about 500 amino acids and have 9 to 11 transmembrane domains. Unlike other SLC36 family members, which are proton-coupled amino acid transporters, SLC36A4 is a high-affinity/low-capacity non-proton-coupled amino acid transporter (Pillai and Meredith, 2011 [PubMed 21097500]).[supplied by OMIM, Feb 2011].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.