Anti-S39AA/ SLC39A10/ LZT-Hs2 monoclonal antibody

Anti-S39AA/ SLC39A10/ LZT-Hs2 antibody for FACS & in-vivo assay

Target products collectionGo to SLC39A10/SLC39A10 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1612-Ab-1/ GM-Tg-hg-MP1612-Ab-2Anti-Human SLC39A10 monoclonal antibodyHuman
GM-Tg-rg-MP1612-Ab-1/ GM-Tg-rg-MP1612-Ab-2Anti-Rat SLC39A10 monoclonal antibodyRat
GM-Tg-mg-MP1612-Ab-1/ GM-Tg-mg-MP1612-Ab-2Anti-Mouse SLC39A10 monoclonal antibodyMouse
GM-Tg-cynog-MP1612-Ab-1/ GM-Tg-cynog-MP1612-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC39A10 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1612-Ab-1/ GM-Tg-felg-MP1612-Ab-2Anti-Feline SLC39A10 monoclonal antibodyFeline
GM-Tg-cang-MP1612-Ab-1/ GM-Tg-cang-MP1612-Ab-2Anti-Canine SLC39A10 monoclonal antibodyCanine
GM-Tg-bovg-MP1612-Ab-1/ GM-Tg-bovg-MP1612-Ab-2Anti-Bovine SLC39A10 monoclonal antibodyBovine
GM-Tg-equg-MP1612-Ab-1/ GM-Tg-equg-MP1612-Ab-2Anti-Equine SLC39A10 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1612-Ab-1/ GM-Tg-hg-MP1612-Ab-2; GM-Tg-rg-MP1612-Ab-1/ GM-Tg-rg-MP1612-Ab-2;
GM-Tg-mg-MP1612-Ab-1/ GM-Tg-mg-MP1612-Ab-2; GM-Tg-cynog-MP1612-Ab-1/ GM-Tg-cynog-MP1612-Ab-2;
GM-Tg-felg-MP1612-Ab-1/ GM-Tg-felg-MP1612-Ab-2; GM-Tg-cang-MP1612-Ab-1/ GM-Tg-cang-MP1612-Ab-2;
GM-Tg-bovg-MP1612-Ab-1/ GM-Tg-bovg-MP1612-Ab-2; GM-Tg-equg-MP1612-Ab-1/ GM-Tg-equg-MP1612-Ab-2
Products NameAnti-SLC39A10 monoclonal antibody
Formatmab
Target NameSLC39A10
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC39A10 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species S39AA/ SLC39A10/ LZT-Hs2 VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1612
    Target NameSLC39A10
    Gene ID57181,227059,363229,696669,478850,101086494,521004,100054925
    Gene Symbol and Synonyms2900042E17Rik,5430433I10,LZT-Hs2,mKIAA1265,SLC39A10,ZIP10
    Uniprot AccessionQ9ULF5
    Uniprot Entry NameS39AA_HUMAN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000196950
    Target ClassificationN/A

    The target: SLC39A10, gene name: SLC39A10, also named as LZT-Hs2. Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A10 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.