Anti-S39A4/ SLC39A4/ AEZ monoclonal antibody

Anti-S39A4/ SLC39A4/ AEZ antibody for FACS & in-vivo assay

Target products collectionGo to SLC39A4/SLC39A4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No.Product NameSpecies Reactivity
GM-Tg-hg-MP1618-Ab-1/ GM-Tg-hg-MP1618-Ab-2Anti-Human SLC39A4 monoclonal antibodyHuman
GM-Tg-rg-MP1618-Ab-1/ GM-Tg-rg-MP1618-Ab-2Anti-Rat SLC39A4 monoclonal antibodyRat
GM-Tg-mg-MP1618-Ab-1/ GM-Tg-mg-MP1618-Ab-2Anti-Mouse SLC39A4 monoclonal antibodyMouse
GM-Tg-cynog-MP1618-Ab-1/ GM-Tg-cynog-MP1618-Ab-2Anti-Cynomolgus/ Rhesus macaque SLC39A4 monoclonal antibodyCynomolgus/ Rhesus macaque
GM-Tg-felg-MP1618-Ab-1/ GM-Tg-felg-MP1618-Ab-2Anti-Feline SLC39A4 monoclonal antibodyFeline
GM-Tg-cang-MP1618-Ab-1/ GM-Tg-cang-MP1618-Ab-2Anti-Canine SLC39A4 monoclonal antibodyCanine
GM-Tg-bovg-MP1618-Ab-1/ GM-Tg-bovg-MP1618-Ab-2Anti-Bovine SLC39A4 monoclonal antibodyBovine
GM-Tg-equg-MP1618-Ab-1/ GM-Tg-equg-MP1618-Ab-2Anti-Equine SLC39A4 monoclonal antibodyEquine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No.GM-Tg-hg-MP1618-Ab-1/ GM-Tg-hg-MP1618-Ab-2; GM-Tg-rg-MP1618-Ab-1/ GM-Tg-rg-MP1618-Ab-2;
GM-Tg-mg-MP1618-Ab-1/ GM-Tg-mg-MP1618-Ab-2; GM-Tg-cynog-MP1618-Ab-1/ GM-Tg-cynog-MP1618-Ab-2;
GM-Tg-felg-MP1618-Ab-1/ GM-Tg-felg-MP1618-Ab-2; GM-Tg-cang-MP1618-Ab-1/ GM-Tg-cang-MP1618-Ab-2;
GM-Tg-bovg-MP1618-Ab-1/ GM-Tg-bovg-MP1618-Ab-2; GM-Tg-equg-MP1618-Ab-1/ GM-Tg-equg-MP1618-Ab-2
Products NameAnti-SLC39A4 monoclonal antibody
Formatmab
Target NameSLC39A4
Protein Sub-locationTransmembrane Protein
Category of antibodyFACS/Biofunctional Antibody
Derivation (species)Mouse
CH1+2+3 Isotype
(Receptor identification)		IgG
Type of Light Chain (VD-LC)N/A
Expression platformMammalian Expression
Bioactivity validationBinding affinity is validated by using flow cytometry with antigen overexpressed cell line. The biofunction of antibodies are validated in cell-based assay (IC50 or EC50 TBD).
TagFc
Products descriptionPre-made anti-SLC39A4 benchmark inhibitory monoclonal antibody(mab) (blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS,ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic)
Purity Purity: ≥95% (SDS-PAGE)
Application Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    CategoryCat No.Products Name
    Target AntigenProducts DevelopingMulti-species S39A4/ SLC39A4/ AEZ VLP (virus-like particle) (Products Developing)


    Target information

    Target IDGM-MP1618
    Target NameSLC39A4
    Gene ID55630,72027,300051,708333,482096,101080686,510951,100147065
    Gene Symbol and Synonyms1600025H15Rik,AEZ,AWMS2,SLC39A4,ZIP4
    Uniprot AccessionQ6P5W5,A0JPN2,Q1KZG0
    Uniprot Entry NameS39A4_HUMAN,S39A4_RAT,S39A4_BOVIN
    Protein Sub-locationTransmembrane Protein
    Category
    DiseaseN/A
    Gene EnsemblENSG00000147804
    Target ClassificationN/A

    The target: SLC39A4, gene name: SLC39A4, also named as AEZ, AWMS2, ZIP4. This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013].



    About Gmab

    GDU
    GDU



    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.

    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.